The mission of the Virginia Commonwealth University (VCU) Massey Cancer Center (MCC) Clinical Research Shared Resource (CRSR) is to support the development and conduct of cancer clinical research and, in particular, clinical trials at the institution. This shared resource is one of the original shared resources established with the Cancer Center Support Grant (CCSG) awarded in 1976. The CRSR provides the following services to all MCC members conducting cancer clinical trials: regulatory compliance, subject recruitment, protocol compliance, data collection and reporting, quality assurance, information dissemination, and reporting on clinical trials activity. In addition, the CRSR provides project management and development of MCC investigator-initiated clinical trials from concept development through activation. The CRSR includes Research Nurses (RNs), Clinical Research Associates (CRAs), Regulatory Coordinators, Quality Control (QC) Coordinator, IT staff. Affiliations Coordinators, and Minority Recruitment staff. Personnel supported by CCSG Protocol-Specific Research (PSR) are in the CRSR.

Public Health Relevance

The Clinical Research Shared Resource provides the infrastructure needed to support the development and conduct of clinical cancer research at MCC. This support helps ensure that clinical trials are developed in an efficient manner, are conducted in compliance with all regulatory requirements, that appropriate data is collected, and that the results are reported in a timely manner.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016059-32
Application #
8559575
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
32
Fiscal Year
2013
Total Cost
$57,596
Indirect Cost
Name
Virginia Commonwealth University
Department
Type
DUNS #
105300446
City
Richmond
State
VA
Country
United States
Zip Code
23298
Ding, Boxiao; Parmigiani, Anita; Divakaruni, Ajit S et al. (2016) Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death. Sci Rep 6:22538
Terracina, Krista P; Graham, Laura J; Payne, Kyle K et al. (2016) DNA methyltransferase inhibition increases efficacy of adoptive cellular immunotherapy of murine breast cancer. Cancer Immunol Immunother 65:1061-73
Alotaibi, Moureq; Sharma, Khushboo; Saleh, Tareq et al. (2016) Radiosensitization by PARP Inhibition in DNA Repair Proficient and Deficient Tumor Cells: Proliferative Recovery in Senescent Cells. Radiat Res 185:229-45
Truchan, Hilary K; Cockburn, Chelsea L; Hebert, Kathryn S et al. (2016) The Pathogen-Occupied Vacuoles of Anaplasma phagocytophilum and Anaplasma marginale Interact with the Endoplasmic Reticulum. Front Cell Infect Microbiol 6:22
Menezes, M E; Das, S K; Minn, I et al. (2016) Detecting Tumor Metastases: The Road to Therapy Starts Here. Adv Cancer Res 132:1-44
Agarwal, Stuti; Bell, Catherine M; Taylor, Shirley M et al. (2016) p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb. Mol Cancer Res 14:66-77
Gewirtz, David A (2016) The Challenge of Developing Autophagy Inhibition as a Therapeutic Strategy. Cancer Res 76:5610-5614
Lafata, Jennifer Elston; Shay, L Aubree; Brown, Richard et al. (2016) Office-Based Tools and Primary Care Visit Communication, Length, and Preventive Service Delivery. Health Serv Res 51:728-45
Korwar, Sudha; Morris, Benjamin L; Parikh, Hardik I et al. (2016) Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP). Bioorg Med Chem 24:2707-15
Ge, Xiuchun; Shi, Xiaoli; Shi, Limei et al. (2016) Involvement of NADH Oxidase in Biofilm Formation in Streptococcus sanguinis. PLoS One 11:e0151142

Showing the most recent 10 out of 413 publications