The Genitourinary Oncology Program consists of a group of basic and clinical investigators collectively focused upon the study and treatment of genitourinary malignancies. The goals of the program include optimal multidisciplinary care through interaction of clinicians of various disciplines, understanding disease biology through the study of basic mechanisms of carcinogenesis and tumor progression, advancement of clinical care through effective implementation of clinical trials, and development of novel preventive and therapeutic strategies through collaboration of basic investigators and clinicians. The program facilitates the achievement of its goals through inter-programmatic seminars and conferences, provision of access to cancer center core facilities and program resources, and acting to identify additional opportunities to maximize the success of collaborations and individual program members. Historically, the main clinical focus of the NYU GU Oncology program has been prostate cancer due to the Department of Urology's longstanding clinical focus in the disease, the large volume of patients, and the number of basic investigators focused in the disease. This remains the most well-developed focus of the program. In the area of bladder cancer, the NYU program has a strong basic research group focused in urothelial biology and urothelial carcinogenesis. While there are ongoing clinical trials in bladder cancer, the program continues to seek additional physician scientists focused in the area of translational and clinical research in bladder cancer. At present, there are 27 program members with appointments in 12 departments within the medical school. 15/27 members are primarily focused in the area of prostate cancer, while 6/27 are focused in trie study of urothelial cancer. The group consists of 9 clinician scientists, 13 basic investigators, and one statistician. Total NCI funding has increased from $1,377,698 to $1,708,288. Membership has increased from 24 to 27. Total publications over the past five years total 211 of which 18% are intra-programmatic and 10% are interprogrammatic.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-31
Application #
8232196
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2011-03-01
Budget End
2012-02-29
Support Year
31
Fiscal Year
2011
Total Cost
$23,332
Indirect Cost
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Berger, Ashton C; Korkut, Anil; Kanchi, Rupa S et al. (2018) A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. Cancer Cell 33:690-705.e9
Harper, Lamia; Balasubramanian, Divya; Ohneck, Elizabeth A et al. (2018) Staphylococcus aureus Responds to the Central Metabolite Pyruvate To Regulate Virulence. MBio 9:
Gowen, Michael F; Giles, Keith M; Simpson, Danny et al. (2018) Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors. J Transl Med 16:82
Llewellyn, Sean R; Britton, Graham J; Contijoch, Eduardo J et al. (2018) Interactions Between Diet and the Intestinal Microbiota Alter Intestinal Permeability and Colitis Severity in Mice. Gastroenterology 154:1037-1046.e2
Pelzek, Adam J; Shopsin, Bo; Radke, Emily E et al. (2018) Human Memory B Cells Targeting Staphylococcus aureus Exotoxins Are Prevalent with Skin and Soft Tissue Infection. MBio 9:
Chiou, Kenneth L; Bergey, Christina M (2018) Methylation-based enrichment facilitates low-cost, noninvasive genomic scale sequencing of populations from feces. Sci Rep 8:1975
Jose, Cynthia C; Jagannathan, Lakshmanan; Tanwar, Vinay S et al. (2018) Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1. Mol Carcinog 57:794-806
Kourtis, Nikos; Lazaris, Charalampos; Hockemeyer, Kathryn et al. (2018) Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia. Nat Med 24:1157-1166
Formenti, Silvia C; Lee, Percy; Adams, Sylvia et al. (2018) Focal Irradiation and Systemic TGF? Blockade in Metastatic Breast Cancer. Clin Cancer Res 24:2493-2504
Snuderl, Matija; Kannan, Kasthuri; Pfaff, Elke et al. (2018) Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma. Nat Commun 9:2868

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