The overall objectives of the Experimental Pathology Shared Resource are to provide NYUCI investigators with quality-controlled, stable and cost-effective services and expertise for the microscopic analysis of human and animal tissues. It is divided into two laboratories: 1) Histopathology and 2) Immunohistochemistry. The Histopathology laboratory provides routine histopathologic services, including tissue preparation, processing, embedding, sectioning and histochemical staining for paraffin and cryoembedded tissues. The Histopathology laboratory also provides whole slide digital imaging and basic microscopy services, and it makes available state-of-the art instrumentation, such as a laser microdissection system. The main role of the Immunohistochemistry laboratory is to develop immunohistochemical protocols for new antibodies (commercial or proprietary) that have not been tested in fresh, frozen or fixed human or animal tissues and cells. It also serves as an immunohistochemical antibody repository with a catalog of over 900 commercial and proprietary antibodies, which is published on the laboratory website. Both laboratories offer one-on-one training as well as formal teaching modules for the Pathobiology and Translational Medicine Graduate Training program and mini-rotations for medical students. The Experimental Pathology laboratories are uniquely positioned as a

Public Health Relevance

The Experimental Pathology Laboratories play a critical role in furthering the research mission of the NYU Cancer Institute (NYUCI). The Experimental Pathology laboratories provide investigators with services and expertise in preparing and evaluating cancer tissue specimens so that basic scientific discoveries can be developed into new ways to detect and treat cancer.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
New York University
New York
United States
Zip Code
Jin, Honglei; Yu, Yonghui; Hu, Young et al. (2015) Divergent behaviors and underlying mechanisms of cell migration and invasion in non-metastatic T24 and its metastatic derivative T24T bladder cancer cell lines. Oncotarget 6:522-36
Zhou, Sherry; Weitzman, Michael; Vilcassim, Ruzmyn et al. (2015) Air quality in New York City hookah bars. Tob Control 24:e193-8
Brocato, Jason; Costa, Max (2015) 10th NTES Conference: Nickel and arsenic compounds alter the epigenome of peripheral blood mononuclear cells. J Trace Elem Med Biol 31:209-13
Cohen, Mitchell D; Vaughan, Joshua M; Garrett, Brittany et al. (2015) Acute high-level exposure to WTC particles alters expression of genes associated with oxidative stress and immune function in the lung. J Immunotoxicol 12:140-53
Ota, Mitsuhiko; Horiguchi, Masahito; Fang, Victoria et al. (2014) Genetic suppression of inflammation blocks the tumor-promoting effects of TGF-? in gastric tissue. Cancer Res 74:2642-51
McKinney, Caleb; Zavadil, Jiri; Bianco, Christopher et al. (2014) Global reprogramming of the cellular translational landscape facilitates cytomegalovirus replication. Cell Rep 6:9-17
Vazquez-Cintron, Edwin J; Vakulenko, Maksim; Band, Philip A et al. (2014) Atoxic derivative of botulinum neurotoxin A as a prototype molecular vehicle for targeted delivery to the neuronal cytoplasm. PLoS One 9:e85517
Jhaveri, Komal; Chandarlapaty, Sarat; Lake, Diana et al. (2014) A phase II open-label study of ganetespib, a novel heat shock protein 90 inhibitor for patients with metastatic breast cancer. Clin Breast Cancer 14:154-60
Wu, Meng; Yang, Feikun; Ren, Zhihua et al. (2014) Identification of the nuclear localization signal of SALL4B, a stem cell transcription factor. Cell Cycle 13:1456-62
Kaneko, Syuzo; Bonasio, Roberto; SaldaƱa-Meyer, Ricardo et al. (2014) Interactions between JARID2 and noncoding RNAs regulate PRC2 recruitment to chromatin. Mol Cell 53:290-300

Showing the most recent 10 out of 491 publications