The overarching goal of the BioRepository Center (BRC) is to facilitate translational research. Tight coordination between surgical staff, pathologists, and BRC enables collection of specimens to fulfill investigators'needs. Our protocols for rapid acquisition of tissue samples allows for preparation of high quality analytes. Patients'rights and privacy by our participation in obtaining and confirming informed consent for tissue collection;guidance with regard to preparation and submission of IRB documents is offered to help ensure compliance. The BRC also promotes collaborations between clinical and basic scientists, and can aid in the design and execution of prospective, hypothesis-driven studies to examine the impact of genetics or treatment on disease progression. By promoting investigators access to appropriate biospecimens, the BRC enhances the ability of NYULMC Cancer Institute members to perform meaningful translational research.

Public Health Relevance

The BioRepository Center (BRC) plays a critical role in promoting translational research at NYU Cancer Institute (NYUCI). By coordinating with surgeons and other clinicians, we help scientists obtain human tissues that they need. This allows for investigations of pathologic processes or novel therapeutics, with the most relevance to human disease, and linking and expanding findings initially discovered in model systems.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-34
Application #
8765174
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-03-01
Budget End
2015-02-28
Support Year
34
Fiscal Year
2014
Total Cost
$128,637
Indirect Cost
$52,745
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Pham, Alissa M; Santa Maria, Felicia Gilfoy; Lahiri, Tanaya et al. (2016) PKR Transduces MDA5-Dependent Signals for Type I IFN Induction. PLoS Pathog 12:e1005489
Kim, Sungheon G; Feng, Li; Grimm, Robert et al. (2016) Influence of temporal regularization and radial undersampling factor on compressed sensing reconstruction in dynamic contrast enhanced MRI of the breast. J Magn Reson Imaging 43:261-9
Zakhar, Joseph; Amrock, Stephen M; Weitzman, Michael (2016) Passive and Active Tobacco Exposure and Children's Lipid Profiles. Nicotine Tob Res 18:982-7
Vogelsang, Matjaz; Martinez, Carlos N; Rendleman, Justin et al. (2016) The Expression Quantitative Trait Loci in Immune Pathways and their Effect on Cutaneous Melanoma Prognosis. Clin Cancer Res 22:3268-80
Pylayeva-Gupta, Yuliya; Das, Shipra; Handler, Jesse S et al. (2016) IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia. Cancer Discov 6:247-55
Lau, Colleen M; Nish, Simone A; Yogev, Nir et al. (2016) Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses. J Exp Med 213:415-31
Reynaud, Olivier; Winters, Kerryanne Veronica; Hoang, Dung Minh et al. (2016) Pulsed and oscillating gradient MRI for assessment of cell size and extracellular space (POMACE) in mouse gliomas. NMR Biomed 29:1350-63
Domènech-Estévez, Enric; Baloui, Hasna; Meng, Xiaosong et al. (2016) Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS. J Neurosci 36:4506-21
Abdu, Yusuff; Maniscalco, Chelsea; Heddleston, John M et al. (2016) Developmentally programmed germ cell remodelling by endodermal cell cannibalism. Nat Cell Biol 18:1302-1310
Canino, Claudia; Cioce, Mario (2016) Isolation of Chemoresistant Cell Subpopulations. Methods Mol Biol 1379:139-50

Showing the most recent 10 out of 878 publications