The overall objectives of the Experimental Pathology Shared Resource are to provide NYUCI investigators with quality-controlled, stable and cost-effective services and expertise for the microscopic analysis of human and animal tissues. It is divided into two laboratories: 1) Histopathology and 2) Immunohistochemistry. The Histopathology laboratory provides routine histopathologic services, including tissue preparation, processing, embedding, sectioning and histochemical staining for paraffin and cryoembedded tissues. The Histopathology laboratory also provides whole slide digital imaging and basic microscopy services, and it makes available state-of-the art instrumentation, such as a laser microdissection system. The main role of the Immunohistochemistry laboratory is to develop immunohistochemical protocols for n ew antibodies (commercial or proprietary) that have not been tested in fresh, frozen or fixed human or animal tissues and cells. It also serves as an immunohistochemical antibody repository with a catalog of over 900 commercial and proprietary antibodies, which is published on the laboratory website. Both laboratories offer one-on-one training as well as formal teaching modules for the Pathobiology and Translational Medicine Graduate Training program and mini-rotations for medical students. The Experimental Pathology laboratories are uniquely positioned as a "bridge" between basic and translational research by promoting resource stability, institutional memory, investigator education, personalized consulting, and interdisciplinary discussions. They also function as a central hub, facilitating inter-shared resource collaborative projects that connect the Biorepository Resource Center and the Translational Research Core Shared Resources with the Proteomics, Genome Technology Center and Flow and Cell Sorting Shared Resources.

Public Health Relevance

The Experimental Pathology Laboratories play a critical role in furthering the research mission of the NYU Cancer Institute (NYUCI). The Experimental Pathology laboratories provide investigators with services and expertise in preparing and evaluating cancer tissue specimens so that basic scientific discoveries can be developed into new ways to detect and treat cancer.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-34
Application #
8765175
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-03-01
Budget End
2015-02-28
Support Year
34
Fiscal Year
2014
Total Cost
$61,512
Indirect Cost
$25,222
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
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