The New York University Cancer Institute (NYUCI) is seeking renewal of its CCSG funding for its 33rd year as an NCI-designated cancer center. Importantly the NYUCI seeks to reacquire comprehensive status given our long track record of accomplishments in population science and our expanded efforts in this area. Major progress has been made in all areas since the appointment of Dr. William L. Carroll as the new Director of NYUCI in 2008. Forty-six new faculty members have been recruited, membership has grown from 172 to 203, and funding has increased to $107.5M, a 35% increase. NCI funding is $23M and other NIH funding is $54M, 8% and 34% increases respectively. NYUCI facilities, under the direct control of Dr. Carroll, have increased by 38% with the opening of an additional ambulatory facility and the planned opening of the Breast Screening Center in spring 2012. Finally, patient volume (in visits) has increased by 35% since 2006 with a total of 170,335 visits at the Clinical Cancer Center, Bellevue Cancer Center, Woodhull Medical Center, Columbus Oncology and the Hassenfeld Children's Center combined in 2011. Accrual to therapeutic studies has grown by 45%, from 13% to almost 20%. Importantly, 68.6% of all accruals are to investigator-initiated studies. In the current application two population-based programs are presented, Environmental and Molecular Carcinogenesis and a new program in Epidemiology and Cancer Control. Dr. Richard Hayes was recruited from the NCI to be Associate Director of Population Sciences and has greatly expanded our efforts in this area. In addition programs in Stem Cell Biology, Cancer Immunology, Growth Control, Melanoma, GU and Breast Cancer are presented. Research in all programs is highly collaborative as demonstrated by increase in collaborative publications from 25% to 38% average across the Research Programs today and the submission of four SPORE applications and one PPG in the past 3 years. Twelve Shared Resources are supported by CCSG funds including three new Shared Resources, RNAi, Biorepository Center and Biomedical Informatics. The Cancer Center Support Grant (CCSG) builds on the many NYU institutional strengths including its presence in the metropolitan campus with a highly diverse faculty, staff and patient population. The NYUCI and CCSG application continues to be a priority of the President of NYU, the Dean and CEO of the NYU-Langone Medical Center, the Boards of both the Hospital and Institute and Community leadership.

National Institute of Health (NIH)
Center Core Grants (P30)
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Study Section
Subcommittee B - Comprehensiveness (NCI)
Program Officer
Ptak, Krzysztof
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New York University
Schools of Medicine
New York
United States
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Jin, Honglei; Yu, Yonghui; Hu, Young et al. (2015) Divergent behaviors and underlying mechanisms of cell migration and invasion in non-metastatic T24 and its metastatic derivative T24T bladder cancer cell lines. Oncotarget 6:522-36
Zhou, Sherry; Weitzman, Michael; Vilcassim, Ruzmyn et al. (2015) Air quality in New York City hookah bars. Tob Control 24:e193-8
Brocato, Jason; Costa, Max (2015) 10th NTES Conference: Nickel and arsenic compounds alter the epigenome of peripheral blood mononuclear cells. J Trace Elem Med Biol 31:209-13
Cohen, Mitchell D; Vaughan, Joshua M; Garrett, Brittany et al. (2015) Acute high-level exposure to WTC particles alters expression of genes associated with oxidative stress and immune function in the lung. J Immunotoxicol 12:140-53
Vazquez-Cintron, Edwin J; Vakulenko, Maksim; Band, Philip A et al. (2014) Atoxic derivative of botulinum neurotoxin A as a prototype molecular vehicle for targeted delivery to the neuronal cytoplasm. PLoS One 9:e85517
Jhaveri, Komal; Chandarlapaty, Sarat; Lake, Diana et al. (2014) A phase II open-label study of ganetespib, a novel heat shock protein 90 inhibitor for patients with metastatic breast cancer. Clin Breast Cancer 14:154-60
Ota, Mitsuhiko; Horiguchi, Masahito; Fang, Victoria et al. (2014) Genetic suppression of inflammation blocks the tumor-promoting effects of TGF-? in gastric tissue. Cancer Res 74:2642-51
McKinney, Caleb; Zavadil, Jiri; Bianco, Christopher et al. (2014) Global reprogramming of the cellular translational landscape facilitates cytomegalovirus replication. Cell Rep 6:9-17
Commisso, Cosimo; Flinn, Rory J; Bar-Sagi, Dafna (2014) Determining the macropinocytic index of cells through a quantitative image-based assay. Nat Protoc 9:182-92
Rao, Raghavendra; Graffeo, Christopher S; Gulati, Rishabh et al. (2014) Interleukin 17-producing ??T cells promote hepatic regeneration in mice. Gastroenterology 147:473-84.e2

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