The goal of the Program is to further our understanding of the biology of breast cancer and to provide scientific support and rationale for preclinical and clinical efforts to improve the detection, prevention, treatment and outcome of breast cancer. Membership, activities and research accomplishments for each of these groups are described below. Breast Cancer Program members work collaboratively both together and with members of other ACC program within these areas, as demonstrated by the transdisciplinary nature of the majority of projects described below.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016520-37
Application #
8567189
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
37
Fiscal Year
2013
Total Cost
$130,182
Indirect Cost
$90,210
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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Zhang, Pingfeng; Leu, Julia I-Ju; Murphy, Maureen E et al. (2014) Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with peptide substrate. PLoS One 9:e103518
Seth, Asha; Ye, Jianming; Yu, Nanjia et al. (2014) Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment. Development 141:538-47
Zhang, Liming; Zhu, Caixia; Guo, Yi et al. (2014) Inhibition of KAP1 enhances hypoxia-induced Kaposi's sarcoma-associated herpesvirus reactivation through RBP-J?. J Virol 88:6873-84

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