The goal of the Patient-Reported Outcomes, Survey and Population Research (PROSPR) facility is to support the assessment of patient-reported outcomes and other behavioral outcomes in studies that span the continuum of research at MDACC. The PROSPR core assists investigators with multiple aspects of designing and implementing Patient Reported Outcome (PRO) data. The PROSPR core offers research support to investigators by maintaining a library of questionnaires, designing data collection procedures for PRO and behavioral studies, providing data collection services, (including face-to-face interviews or questionnaire administration in the clinic, telephone interviewing, and mailed surveys) and providing efficient data entry of the collected PRO data. The PROSPR data management team develops information systems to assist investigators in managing study participants and data. The team also develops recruitment and participant tracking databases, creates data entry databases for PRO questionnaire data that have double entry systems for accuracy checking, as well as built-in range and validity checks, and provides analysis datasets for project statisticians, which includes cleaning and scoring the data. The data management team can create tools for automating the assignment of participants to study conditions, for a simple randomization or a form of adaptive randomization called minimization, which is similar to stratification. The PROSPR core facility is housed in 688 square feet of office space in the Cancer Prevention Building within the Department of Behavioral Science. The facility has 9 staff members, which include the director, co-director, core manager, 2 research coordinators, a statistical analyst, and 3 data managers. Over the past 4 years, the PROSPR core has delivered over 9,400 hours of service to 87 users, of which 47% have been peerreviewed funded. In this period, the PROSPR core has provided assistance to 15 programs;Behavioral and Health Disparities accounted for 56% of the utilization, followed by GU, Gynecological, Gl and Breast Cancers which account for 24%. In the future, the PROSPR core intends to 1) offer web-based surveys, and computer adaptive testing (CAT) as the technology becomes available;2) to more fully utilize CaBIG, which is expanding to include more population science research and;3) to develop training opportunities for investigators and research staff to increase their skills and knowledge related to research involving PRO data.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Texas MD Anderson Cancer Center
United States
Zip Code
Yedururi, Sireesha; Terpenning, Silanath; Gupta, Sanjay et al. (2017) Radiofrequency Ablation of Hepatic Tumor: Subjective Assessment of the Perilesional Vascular Network on Contrast-Enhanced Computed Tomography Before and After Ablation Can Reliably Predict the Risk of Local Recurrence. J Comput Assist Tomogr 41:607-613
Montalban-Bravo, G; Huang, X; Jabbour, E et al. (2017) A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials. Leukemia 31:318-324
Tadros, Audree B; Smith, Benjamin D; Shen, Yu et al. (2017) Ductal Carcinoma In Situ and Margins <2?mm: Contemporary Outcomes With Breast Conservation. Ann Surg :
Ikoma, Naruhiko; Raghav, Kanwal; Chang, George (2017) An Update on Randomized Clinical Trials in Metastatic Colorectal Carcinoma. Surg Oncol Clin N Am 26:667-687
Alhuraiji, Ahmad; Jain, Nitin (2017) Immunofluorescence staining with an antipromyelocytic leukemia antibody for a rapid diagnosis of acute promyelocytic leukemia. Hematol Oncol Stem Cell Ther 10:33-34
Lin, Heather Y; Bedrosian, Isabelle; Babiera, Gildy V et al. (2017) Using the National Cancer Data Base for quality evaluation to assess adherence to treatment guidelines for nonmetastatic inflammatory breast cancer. Cancer 123:2618-2625
Rozovski, Uri; Harris, David M; Li, Ping et al. (2017) Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex. Mol Cancer Res 15:610-618
Masarova, Lucia; Kantarjian, Hagop; Garcia-Mannero, Guillermo et al. (2017) Harnessing the Immune System Against Leukemia: Monoclonal Antibodies and Checkpoint Strategies for AML. Adv Exp Med Biol 995:73-95
Palacios, Cristina; Daniel, Carrie R; Tirado-Gómez, Maribel et al. (2017) Dietary Patterns in Puerto Rican and Mexican-American Breast Cancer Survivors: A Pilot Study. J Immigr Minor Health 19:341-348
Gunther, Jillian R; Chadha, Awalpreet S; Shin, Ui Sup et al. (2017) Preoperative radiation dose escalation for rectal cancer using a concomitant boost strategy improves tumor downstaging without increasing toxicity: A matched-pair analysis. Adv Radiat Oncol 2:455-464

Showing the most recent 10 out of 10289 publications