The Biostatistics Shared Resource (BSR) supports the research of 43% (n=62/144) of all program-aligned members of the St. Jude Comprehensive Cancer Center (SJCCC), of which 61% (n=38/62) have cancer related peer-reviewed funding, and 39% (n=24/62) hold cancer-related, non-peer-reviewed funding. These SJCCC members were drawn from all five of our Center Programs. The resource provides collaborative, statistical support to Center members for peer-reviewed, funded grants and statistical designs for institutional clinical, translational and pre-clinical studies, as well as for laboratory investigations. BSR biostatisticians are active members of SJCCC Programs and provide members with access to state-of-the-art, innovative statistical science;a centralized randomization system;access to SAS for Windows;technical support for a web-based distributed data management system. The Cancer Center Support Grant provides critical funding that is necessary to ensure centralization of function and stability of support;thus, permitting cost effective, timely collaborations.

Public Health Relevance

The Biostatistics Shared Resource provides the SJCCC with outstanding support for the appropriate statistical design and analysis of both clinical and laboratory cancer research. The input of this resource is critical to ensure that all study objectives are addressed with statistical confidence and subsequent publications are supported by appropriate statistical analyses providing valid inferences.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA021765-35
Application #
8634431
Study Section
Subcommittee G - Education (NCI)
Project Start
1997-04-01
Project End
2019-02-28
Budget Start
2014-06-09
Budget End
2015-02-28
Support Year
35
Fiscal Year
2014
Total Cost
$177,500
Indirect Cost
$76,861
Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105
Wang, Xusheng; Jones, Drew R; Shaw, Timothy I et al. (2018) Target-Decoy-Based False Discovery Rate Estimation for Large-Scale Metabolite Identification. J Proteome Res 17:2328-2334
Sabin, N D; Cheung, Y T; Reddick, W E et al. (2018) The Impact of Persistent Leukoencephalopathy on Brain White Matter Microstructure in Long-Term Survivors of Acute Lymphoblastic Leukemia Treated with Chemotherapy Only. AJNR Am J Neuroradiol 39:1919-1925
Brinkman, Tara M; Recklitis, Christopher J; Michel, Gisela et al. (2018) Psychological Symptoms, Social Outcomes, Socioeconomic Attainment, and Health Behaviors Among Survivors of Childhood Cancer: Current State of the Literature. J Clin Oncol 36:2190-2197
Fuentes-Alabi, Soad; Bhakta, Nickhill; Vasquez, Roberto Franklin et al. (2018) The cost and cost-effectiveness of childhood cancer treatment in El Salvador, Central America: A report from the Childhood Cancer 2030 Network. Cancer 124:391-397
Bouchard, Jill J; Otero, Joel H; Scott, Daniel C et al. (2018) Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments. Mol Cell 72:19-36.e8
Flerlage, Jamie E; Metzger, Monika L; Bhakta, Nickhill (2018) The management of Hodgkin lymphoma in adolescents and young adults: burden of disease or burden of choice? Blood 132:376-384
Hijano, Diego R; Siefker, David T; Shrestha, Bishwas et al. (2018) Type I Interferon Potentiates IgA Immunity to Respiratory Syncytial Virus Infection During Infancy. Sci Rep 8:11034
Follis, Ariele Viacava; Llambi, Fabien; Kalkavan, Halime et al. (2018) Regulation of apoptosis by an intrinsically disordered region of Bcl-xL. Nat Chem Biol 14:458-465
Zheng, Daniel J; Krull, Kevin R; Chen, Yan et al. (2018) Long-term psychological and educational outcomes for survivors of neuroblastoma: A report from the Childhood Cancer Survivor Study. Cancer 124:3220-3230
Fatima, Soghra; Zhou, Sheng; Sorrentino, Brian P (2018) Marking of definitive HSC precursors in E7.5-E8.5 embryos using an Abcg2-CreER lineage-tracing mouse model. Exp Hematol 65:29-33

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