Nutrition Nutrition is the process by which the human body utilizes food for the normal functioning of every organ and tissue. Food provides nutrients and numerous other bioactive compounds, many of which have been specifically linked to cellular and molecular events and activities that have been identified in the development and progression of cancer. This resource contributes to the core scientific mission that defines the primary goals of the Center's efforts and enables Cancer Center members to have access to state-of-the-art nutritional services. Components of the Nutrition Shared Resource are: Detailed dietary assessment and monitoring, including use of computer-assisted telephone-based 24-hour dietary recall methodology, food frequency questionnaires, and screeners and focused recalls that target selected food groups and nutrients of interest; nutrition-specialized biochemical laboratory assessment technologies, including quantitative measures of nutrients, bioactive food components, and relevant metabolites in biological samples;telephone-based dietary counseling, provided by trained and experienced counselors who use protocol-driven methods;and consultative services relevant to nutritional assessment and diet intervention methodologies. Cancer Center members are engaged in a wide range of research relevant to nutrition, including studies that address etiologic relationships between diet and cancer, modifications in diet as an effort to reduce the risk and progression of cancer, community-based interventions to promote healthy eating behavior, and laboratory and experimental responses to administering compounds that may affect nutritional status and related metabolic factors. Areas of current and future focus for the service are contributions to the improvement of dietary assessment methodologies, especially when aimed toward minority groups;contributions to improved food content and dietary supplement content databases;and the development and testing of newly proposed dietary biomarkers, especially those appropriate for measurement of status for bioactive food components.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA023100-27S9
Application #
8530404
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2011-05-01
Budget End
2013-04-30
Support Year
27
Fiscal Year
2013
Total Cost
$154,055
Indirect Cost
$53,192
Name
University of California San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Sen, Supriya; Langiewicz, Magda; Jumaa, Hassan et al. (2015) Deletion of serine/arginine-rich splicing factor 3 in hepatocytes predisposes to hepatocellular carcinoma in mice. Hepatology 61:171-83
Hoffmann, Hanne M; Tamrazian, Anika; Xie, Huimin et al. (2014) Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice. Endocrinology 155:4043-53
Hartman, Lisa L R; Crawford, John R; Makale, Milan T et al. (2014) Pediatric phase II trials of poly-ICLC in the management of newly diagnosed and recurrent brain tumors. J Pediatr Hematol Oncol 36:451-7
Williams, Richard T; Barnhill, Lisa M; Kuo, Huan-Hsien et al. (2014) Chimeras of p14ARF and p16: functional hybrids with the ability to arrest growth. PLoS One 9:e88219
Huang, Carlos P; Fofana, Mariama; Chan, Jefferson et al. (2014) Copper transporter 2 regulates intracellular copper and sensitivity to cisplatin. Metallomics 6:654-61
Paolini, Paul; Pick, Daniel; Lapira, Jennifer et al. (2014) Developmental and extracellular matrix-remodeling processes in rosiglitazone-exposed neonatal rat cardiomyocytes. Pharmacogenomics 15:759-74
Goellner, Eva M; Smith, Catherine E; Campbell, Christopher S et al. (2014) PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair. Mol Cell 55:291-304
Glidewell-Kenney, Christine A; Trang, Crystal; Shao, Paul P et al. (2014) Neurokinin B induces c-fos transcription via protein kinase C and activation of serum response factor and Elk-1 in immortalized GnRH neurons. Endocrinology 155:3909-19
Jiang, P; Mukthavaram, R; Chao, Y et al. (2014) In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells. Br J Cancer 111:1562-71
Jacques, Bonnie E; Montgomery 4th, William H; Uribe, Phillip M et al. (2014) The role of Wnt/*-catenin signaling in proliferation and regeneration of the developing basilar papilla and lateral line. Dev Neurobiol 74:438-56

Showing the most recent 10 out of 359 publications