The Microscopy Shared Resource provides both basic and advanced tools, as well as education and training, to Cancer Center Members, thus enabling them to carry out their functions in the most efficient and cost-effective manner. Cancer research encompasses a broad range of investigations ranging from the behavior of cancer cells in the body, to the changes in cancer cells at the molecular level. This requires a spectrum of tools that enable imaging of individual cells and their interactions, both at the level of the whole animal, as well as at the level of molecules inside the cells. Since it is beyond the scope of individual laboratories to invest resources in all of their imaging needs, the shared resource provides a viable alternative. By bringing together investigators with diverse interests and common goals, it fosters a spirit of collaboration and cooperation that leads us closer to the ultimate goals of cancer treatment and cure.
The Microscopy Share Resource plays a critical role in cancer diagnosis and treatment. It supports investigations into the growth and metastatic properties of cancer cells as well as the expression and functions of cancer related gene products. It is also important in the evaluation of technologies for cancer treatment, especially ones that target residual cancer cells that might escape conventional therapies.
|Singh, Siddharth; Loomba, Rohit (2018) Role of two-dimensional shear wave elastography in the assessment of chronic liver diseases. Hepatology 67:13-15|
|Hartman, Sheri J; Nelson, Sandahl H; Myers, Emily et al. (2018) Randomized controlled trial of increasing physical activity on objectively measured and self-reported cognitive functioning among breast cancer survivors: The memory & motion study. Cancer 124:192-202|
|Hoffmann, Hanne M; Gong, Ping; Tamrazian, Anika et al. (2018) Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on the GnRH promoter controls Gnrh1 expression levels in a GnRH neuron maturation specific manner. Mol Cell Endocrinol 461:143-154|
|Liu, Xuxiang; Cao, Minghui; Palomares, Melanie et al. (2018) Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts. Breast Cancer Res 20:127|
|Huang, Justin K; Carlin, Daniel E; Yu, Michael Ku et al. (2018) Systematic Evaluation of Molecular Networks for Discovery of Disease Genes. Cell Syst 6:484-495.e5|
|Kalyanaraman, Hema; Schwaerzer, Gerburg; Ramdani, Ghania et al. (2018) Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes. Diabetes 67:607-623|
|Hartman, Sheri J; Marinac, Catherine R; Cadmus-Bertram, Lisa et al. (2018) Sedentary Behaviors and Biomarkers Among Breast Cancer Survivors. J Phys Act Health 15:1-6|
|Wu, Yan; Tamayo, Pablo; Zhang, Kun (2018) Visualizing and Interpreting Single-Cell Gene Expression Datasets with Similarity Weighted Nonnegative Embedding. Cell Syst 7:656-666.e4|
|Dow, Michelle; Pyke, Rachel M; Tsui, Brian Y et al. (2018) Integrative genomic analysis of mouse and human hepatocellular carcinoma. Proc Natl Acad Sci U S A 115:E9879-E9888|
|Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin et al. (2018) Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature 558:301-306|
Showing the most recent 10 out of 862 publications