The program leaders and co-leaders of the Purdue University Center for Cancer Research includes Drs. Elizabeth Taparowsky and David Riese function as leader and co-leader, respectively, of the Cell Growth and Differentiation Program. Drs. Cynthia Stauffacher and David Thompson are leader and co-leader, respectively, of the Chemical and Structural Biology Program. Drs. Richard Gibbs and Deborah Knapp are leader and co-leader of the Medicinal Chemistry Program and Drs Donald Bergstrom and Alex Wei are leader and co-leader of the Drug Delivery and Molecular Sensing Program. These leaders have distinguished and highly collaborative research laboratories and have functioned to guide their respective programs. They organize programmatic meetings, set goals, mentor members and encourage transdisciplinary participation in research efforts. Further, all serve on the primary decision making body of the Center, the Executive Committee. In this capacity all provide input on major decision of the Center and thus, contribute to determining the future mission of the Center.
The program leaders and co-leaders provide vision, resources and organizational capacity for the Center that enables the pursuit of collaborative research. The collaborative efforts bring together scientists from many disciplines to address cancer-related problems. Throught these transdisciplinary investigations, novel discoveries are made that lead to improvement in early detection and care of cancer patients.
|Orellana, Esteban A; Tenneti, Srinivasarao; Rangasamy, Loganathan et al. (2017) FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer. Sci Transl Med 9:|
|Wyatt-Johnson, Season K; Herr, Seth A; Brewster, Amy L (2017) Status Epilepticus Triggers Time-Dependent Alterations in Microglia Abundance and Morphological Phenotypes in the Hippocampus. Front Neurol 8:700|
|Han, Ning; Pang, Liang; Xu, Jun et al. (2017) Development of Surface-Variable Polymeric Nanoparticles for Drug Delivery to Tumors. Mol Pharm 14:1538-1547|
|Wu, M-J; Kim, M R; Chen, Y-S et al. (2017) Retinoic acid directs breast cancer cell state changes through regulation of TET2-PKC? pathway. Oncogene 36:3193-3206|
|Jang, Yumi; Rao, Xiayu; Jiang, Qing (2017) Gamma-tocotrienol profoundly alters sphingolipids in cancer cells by inhibition of dihydroceramide desaturase and possibly activation of sphingolipid hydrolysis during prolonged treatment. J Nutr Biochem 46:49-56|
|Li, Jie; Wang, Ruixin; Kong, Yifan et al. (2017) Targeting Plk1 to Enhance Efficacy of Olaparib in Castration-Resistant Prostate Cancer. Mol Cancer Ther 16:469-479|
|Wang, Siwen; Xing, Zheng; Pascuzzi, Pete E et al. (2017) Metabolic Adaptation to Nutrients Involves Coregulation of Gene Expression by the RNA Helicase Dbp2 and the Cyc8 Corepressor in Saccharomyces cerevisiae. G3 (Bethesda) 7:2235-2247|
|Yue, Feng; Bi, Pengpeng; Wang, Chao et al. (2017) Pten is necessary for the quiescence and maintenance of adult muscle stem cells. Nat Commun 8:14328|
|Li, Guo; Low, Philip S (2017) Synthesis and evaluation of a ligand targeting the ? and ? opioid receptors for drug delivery to lung cancer. Bioorg Med Chem Lett 27:2074-2078|
|Chen, I-Hsuan; Xue, Liang; Hsu, Chuan-Chih et al. (2017) Phosphoproteins in extracellular vesicles as candidate markers for breast cancer. Proc Natl Acad Sci U S A 114:3175-3180|
Showing the most recent 10 out of 370 publications