The senior leadership of the Purdue University Center for Cancer Research includes Dr. Timothy L. Ratliff, Center director, and Dr. Marietta Harrison, associate director of the Center. Dr. Ratliff was a leader in the University of Iowa Holden Comprehensive Cancer Center prior to joining the Purdue University Center for Cancer Research. Drs. Ratliff and Harrison each have over ten years of experience in Cancer Center leadership positions. They work together to strengthen the Center's position in the University and advance the cancer research effort on the Purdue campus. They also provide an integrated scientific vision for the future of the Center. Support is requested at a level of 50% effort for Dr. Ratliff and 30% effort for Dr. Harrison.
Senior leadership provides vision for future research directions and encourages transdisciplinary collaborations. The coordinated effort of leadership enhances research and provides the resources for improved discovery.
|Krisenko, Mariya O; Cartagena, Alexander; Raman, Arvind et al. (2015) Nanomechanical property maps of breast cancer cells as determined by multiharmonic atomic force microscopy reveal Syk-dependent changes in microtubule stability mediated by MAP1B. Biochemistry 54:60-8|
|Cho, Eun Jung; Sun, Bo; Doh, Kyung-Oh et al. (2015) Intraperitoneal delivery of platinum with in-situ crosslinkable hyaluronic acid gel for local therapy of ovarian cancer. Biomaterials 37:312-9|
|Bai, Yu; Davis, Dexter C; Dai, Mingji (2014) Synthesis of tetrahydropyran/tetrahydrofuran-containing macrolides by palladium-catalyzed alkoxycarbonylative macrolactonizations. Angew Chem Int Ed Engl 53:6519-22|
|Chao, Chi-Hong; Chang, Chao-Ching; Wu, Meng-Ju et al. (2014) MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis. J Clin Invest 124:3093-106|
|Lee, Kyuwan; Cui, Yi; Lee, Luke P et al. (2014) Quantitative imaging of single mRNA splice variants in living cells. Nat Nanotechnol 9:474-80|
|Yang, Yang; Haskins, Christopher W; Zhang, Wandi et al. (2014) Divergent total syntheses of lyconadins A and C. Angew Chem Int Ed Engl 53:3922-5|
|Ghosh, Arun K; Osswald, Heather L (2014) BACE1 (?-secretase) inhibitors for the treatment of Alzheimer's disease. Chem Soc Rev 43:6765-813|
|Byun, Alexander J; Hung, Kenneth E; Fleet, James C et al. (2014) Colon-specific tumorigenesis in mice driven by Cre-mediated inactivation of Apc and activation of mutant Kras. Cancer Lett 347:191-5|
|Emmert, Dana; Campos, Christopher R; Ward, David et al. (2014) Reversible dimers of the atypical antipsychotic quetiapine inhibit p-glycoprotein-mediated efflux in vitro with increased binding affinity and in situ at the blood-brain barrier. ACS Chem Neurosci 5:305-17|
|Hrycyna, Christine A; Summers, Robert L; Lehane, Adele M et al. (2014) Quinine dimers are potent inhibitors of the Plasmodium falciparum chloroquine resistance transporter and are active against quinoline-resistant P. falciparum. ACS Chem Biol 9:722-30|
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