The Center Director has the authority and responsibility to define the Center's annual and long-term priorities and activities. Senior Leadership, Program Leaders and Faculty are significant contributors in the planning and evaluation process, as are Internal Advisory Groups consisting of the Program Planning Group (PPG), the Shared Resources Team, and the Administrative Team. External Advisory Groups consisting of the Cancer Center's Scientific Advisory Board (CCSAB) and Advisor for the Cancer Center Administration provide advice and new perspectives on current activities and future directions. Faculty provide input to planning and evaluation activities through Annual Reviews, Annual Faculty Retreat, and monthly Program Meetings. In these meetings. Program Leaders summarize the outcome of PPG discussions and actively solicit faculty feedback. This enhances the communication of Center goals to the faculty in a timely manner, and actively incorporates faculty opinions as part of developing plans. The Shared Resources Team evaluates the services of the core facilities in monthly meetings that are open to all faculty, and makes recommendations about future service needs and directions, including potential new instrumentation. Based on these sources of input, the PPG formulates specific annual goals and long-term plans, and presents these goals to CCSAB each spring. In parallel. Cancer Center's Administrative Team identifies mechanisms via which Center members can support these goals, through incentives such as pilot grant funding, development of core facilities and new instrumentation, and recruitment of new collaborating faculty. Once the goals are set, PPG and its ad hoc Task Forces consisting of several faculty members, including Recruitment and Pilot Project Committees, are primary drivers for implementing the goals that bring to the Center new technologies, new areas of research, and opportunities for scientific collaborations. Approved goals are distributed to all faculty and discussed in subsequent Program and Center meetings, to encourage Center-wide participation via various incentive mechanisms described above, and to assure continuous and iterative feedback from faculty on Center activities. Funding in the total amount of $16,000 is requested for the costs associated with the External Advisory Group activities, which include annual CCSAB meeting and annual Center Administration review. $20,000 is requested for the Annual Faculty Retreat. Institutional funds will be utilized to cover Internal Advisory Group activities, including monthly PPG, Administrative Team and Shared Resources Team meetings, as well as monthly Program meetings and Seminar Series.
A strong planning and evaluation structure will permit the Center to identify both short-term and long-term scientific goals, to monitor progress toward meeting goals, and to plan for the facilities and financial support needed to meet these goals, thereby maximizing the scientific environment, collaborations and productivity of the Cancer Center Investigators.
|Lechtenberg, Bernhard C; Rajput, Akhil; Sanishvili, Ruslan et al. (2016) Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation. Nature 529:546-50|
|Zhong, Zhenyu; Umemura, Atsushi; Sanchez-Lopez, Elsa et al. (2016) NF-ÎºB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria. Cell 164:896-910|
|Olson, Erika J; Lechtenberg, Bernhard C; Zhao, Chunxia et al. (2016) Modifications of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor To Achieve High Plasma Stability. ACS Med Chem Lett 7:841-6|
|Tinoco, Roberto; Carrette, Florent; Barraza, Monique L et al. (2016) PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion. Immunity 44:1190-203|
|Zhao, Wei; Mazar, Joseph; Lee, Bongyong et al. (2016) The Long Noncoding RNA SPRIGHTLY Regulates Cell Proliferation in Primary Human Melanocytes. J Invest Dermatol 136:819-28|
|Singec, Ilyas; Crain, Andrew M; Hou, Junjie et al. (2016) Quantitative Analysis of Human Pluripotency and Neural Specification by In-Depth (Phospho)Proteomic Profiling. Stem Cell Reports 7:527-42|
|McQuary, Philip R; Liao, Chen-Yu; Chang, Jessica T et al. (2016) C.Â elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension. Cell Rep 14:2059-67|
|Moscat, Jorge; Karin, Michael; Diaz-Meco, Maria T (2016) p62 in Cancer: Signaling Adaptor Beyond Autophagy. Cell 167:606-609|
|Miletic, Ana V; Jellusova, Julia; Cato, Matthew H et al. (2016) Essential Role for Survivin in the Proliferative Expansion of Progenitor and Mature B Cells. J Immunol 196:2195-204|
|Koh, Mei Yee; Gagea, Mihai; Sargis, Timothy et al. (2016) A new HIF-1Î±/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice. Hepatology 63:1576-91|
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