The Jackson Laboratory (TJL) Cancer Center program planning and evaluation process is intrinsic to the continuous strategic planning effort for the parent institution. The institutional plan lays out five-year objectives for growth in research, education, and training, which guide budgetary decisions, faculty recruiting, facilities design and construction, resource and service expansion, equipment purchases, and other activities. The Cancer Center receives priority in all such decisions. Drs. Woychik and Knowles are members of the executive-level Senior Management Team, which advises Dr. Woychik on the administration of TJL and the Cancer Center. Drs. Woychik and Knowles are also advised by the Cancer Center Internal Advisory Committee composed of an interdisciplinary group of Cancer Center members and senior managers. The Scientific Advisory Council composed of six TJL faculty members, advises the Director on long-range planning, evaluation, and operation of TJL research mission, including the Cancer Center. An annual Scientific Staff retreat serves as the forum for planning that involves all Cancer Center members. External advice and evaluation are provided by the Board of Scientific Overseers. These planning and evaluation functions are supported through institutional funds. The Seminar Program serves the planning function by organizing a series of presentations by invited speakers. Speakers visit for up to three days, present seminars of Cancer Center-wide interest, and meet individually with Cancer Center members with related research interests. Drs. Woychik and Knowles use these opportunities to gain advice on long-range planning for the Center and to promote interdisciplinary collaborations. CCSG support is requested for sponsoring distinguished speakers of special relevance to cancer research. Priority will be given to speakers who can open doors for translational research partnerships and/or collaborations with other NCI-designated cancer centers or NCI-funded initiatives. Goals for the Cancer Center for the next grant cycle include: hiring one to two new Cancer Center members annually; adding research space for bioinformatics and computational biology; establishing interdisciplinary and transdisciplinary inter-institutional collaborations locally, nationally, and internationally to promote translational research; providing facilities and pioneering methods for continued improvements in efficiency of genetic resources; supporting research growth with requisite expansion and technological improvements in the Scientific Services; expanding the educational programs that serve the Center's outreach goals; and securing the necessary bandwidth and infrastructure to support anticipated data transmission needs.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA034196-28S2
Application #
8558789
Study Section
Subcommittee G - Education (NCI)
Project Start
1997-08-01
Project End
2013-06-30
Budget Start
2012-08-03
Budget End
2013-06-30
Support Year
28
Fiscal Year
2012
Total Cost
$5,250
Indirect Cost
$2,250
Name
Jackson Laboratory
Department
Type
DUNS #
042140483
City
Bar Harbor
State
ME
Country
United States
Zip Code
04609
Jung, Seung-Hyun; Kim, Min Sung; Lee, Sung-Hak et al. (2016) Whole-exome sequencing identifies recurrent AKT1 mutations in sclerosing hemangioma of lung. Proc Natl Acad Sci U S A 113:10672-7
Qin, Wenning; Kutny, Peter M; Maser, Richard S et al. (2016) Generating Mouse Models Using CRISPR-Cas9-Mediated Genome Editing. Curr Protoc Mouse Biol 6:39-66
Tai, Derek J C; Ragavendran, Ashok; Manavalan, Poornima et al. (2016) Engineering microdeletions and microduplications by targeting segmental duplications with CRISPR. Nat Neurosci 19:517-22
Sundberg, John P; Pratt, C Herbert; Silva, Kathleen A et al. (2016) Dermal lymphatic dilation in a mouse model of alopecia areata. Exp Mol Pathol 100:332-6
Parvanov, Emil D; Tian, Hui; Billings, Timothy et al. (2016) PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis. Mol Biol Cell :
Ali, Riyasat; Babad, Jeffrey; Follenzi, Antonia et al. (2016) Genetically modified human CD4(+) T cells can be evaluated in vivo without lethal graft-versus-host disease. Immunology 148:339-51
Ishimura, Ryuta; Nagy, Gabor; Dotu, Ivan et al. (2016) Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation. Elife 5:
Jangalwe, Sonal; Shultz, Leonard D; Mathew, Anuja et al. (2016) Improved B cell development in humanized NOD-scid IL2Rγ(null) mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3. Immun Inflamm Dis 4:427-440
Samanta, S; Sun, H; Goel, H L et al. (2016) IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG. Oncogene 35:1111-21
Korstanje, Ron; Deutsch, Konstantin; Bolanos-Palmieri, Patricia et al. (2016) Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria. J Am Soc Nephrol 27:3271-3277

Showing the most recent 10 out of 958 publications