The Biostatistics &Bioinformatics Core Facility is a shared resource that provides statistical, bioinformatics, and research informatics support to the Case Comprehensive Cancer Center. The Core includes biostatistics, bioinformatics, and research informatics faculty and staff from Case Western Reserve University and Cleveland Clinic.
Specific aims of the Biostatistics &Bioinformatics Core Facility are: 1) To provide statistical, bioinformatics, and research informatics support to Case CCC members in the design, planning, conduct analysis, and reporting of research studies;2) To ensure that Cancer Center studies are designed, conducted and monitored properly by reviewing all protocols and proposals, and participating in ongoing quality control and data and safety monitoring of ongoing studies;3) To provide and coordinate informatics support to the OnCore clinical trials management database and other research databases and serve as a base for research informatics in the Case CCC. The primary focus of the portion of the BBCF funded by the CCSG is to provide support for proposal development, pilot studies, or other NIH-funded peer-reviewed studies. Extensive data analytic efforts are supported by funding of core members on grants or charge-back. The Biostatistics and Bioinformatics Core Facility brings together expertise and intellectual resources in biostatistics, bioinformatics, clinical research informatics, clinical trials, epidemiology, and statistical computing.
The Case Comprehensive Cancer Center is Northeast Ohio's only NCI designated comprehensive cancer center providing bench-to-bedside medical research involving partnerships between basic, clinical and population scientists to speed translation of laboratory discoveries into new prevention/intervention and cancer treatments.
|Levinson, Kimberly L; Jernigan, Amelia M; Flocke, Susan A et al. (2016) Intimate Partner Violence and Barriers to Cervical Cancer Screening: A Gynecologic Oncology Fellow Research Network Study. J Low Genit Tract Dis 20:47-51|
|Cooper, Gregory S; Kou, Tzuyung D; Schluchter, Mark D et al. (2016) Changes in Receipt of Cancer Screening in Medicare Beneficiaries Following the Affordable Care Act. J Natl Cancer Inst 108:|
|Wiechert, Andrew; Saygin, Caner; Thiagarajan, Praveena S et al. (2016) Cisplatin induces stemness in ovarian cancer. Oncotarget 7:30511-22|
|Somasegar, Sahana; Li, Li; Thompson, Cheryl L (2016) No association of reproductive risk factors with breast cancer tumor grade. Eur J Cancer Prev :|
|Kenyon, Jonathan; Nickel-Meester, Gabrielle; Qing, Yulan et al. (2016) Epigenetic Loss of MLH1 Expression in Normal Human Hematopoietic Stem Cell Clones is Defined by the Promoter CpG Methylation Pattern Observed by High-Throughput Methylation Specific Sequencing. Int J Stem Cell Res Ther 3:|
|Dowlati, A; Lipka, M B; McColl, K et al. (2016) Clinical correlation of extensive-stage small-cell lung cancer genomics. Ann Oncol 27:642-7|
|Markowitz, Sanford D; Nock, Nora L; Schmit, Stephanie L et al. (2016) A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis. PLoS One 11:e0146435|
|Wang, Y; Deng, O; Feng, Z et al. (2016) RNF126 promotes homologous recombination via regulation of E2F1-mediated BRCA1 expression. Oncogene 35:1363-72|
|Doherty, Mary R; Smigiel, Jacob M; Junk, Damian J et al. (2016) Cancer Stem Cell Plasticity Drives Therapeutic Resistance. Cancers (Basel) 8:|
|Blum, Andrew E; Venkitachalam, Srividya; Guo, Yan et al. (2016) RNA Sequencing Identifies Transcriptionally Viable Gene Fusions in Esophageal Adenocarcinomas. Cancer Res 76:5628-5633|
Showing the most recent 10 out of 1148 publications