Abstract

CANCER RESEARCH CAREER ENHANCEMENT AND RELATED ACTIVITIES PROJECT SUMMARY/ABSTRACT The Cancer Research Career Enhancement and Related Activities are centered in the Case Comprehensive Cancer Center (Case CCC) Office of Cancer Trainee Education and Research (OCTER), which coordinates existing research education and training activities across the consortium?s institutions, and develops new educational initiatives with emphasis on integrating cancer researchers and health care professionals. Case CCC supported programs have facilitated career enrichment activities for 1,622 cancer trainees during the last cycle, spanning career stages from high school students through junior faculty. The impact of these efforts are evidenced by: 1) the portfolio of peer-reviewed training grants in cancer research and clinical training; 2) the high-impact basic and clinical science performed by Center trainees; 3) robust trainee involvement in Center- sponsored career enrichment activities; 4) successful career advancement for all Case CCC trainees; 5) coordination of Center-wide research education and training activities by the Cancer Education and Research Committee (CERC); and 6) Center efforts to engage underrepresented minority (URM) groups at all levels, including high school and undergraduate students, to enter cancer-oriented biomedical scientific research and healthcare professions. To maintain excellence and expand Center cancer research career enrichment activities, the OCTER has developed the following three specific aims that will carry it forward in the next grant cycle:
Aim 1 : Provide cancer research career enrichment activities across the continuum of trainees.
Aim 2 : Coordinate Center-wide cancer education and training activities.
Aim 3 : Integrate cancer research mentoring and training of biomedical scientists and healthcare professionals. The Case CCC strives to provide rigorous training in cancer research as well as career enhancement activities that prepare all trainees for productive careers as biomedical cancer researchers or healthcare professionals.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA043703-28
Application #
9488757
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2018-05-10
Budget End
2019-03-31
Support Year
28
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106

  Publications

Liu, Xia; Taftaf, Rokana; Kawaguchi, Madoka et al. (2018) Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models. Cancer Discov :
Belur Nagaraj, Anil; Joseph, Peronne; Kovalenko, Olga et al. (2018) Evaluating class III antiarrhythmic agents as novel MYC targeting drugs in ovarian cancer. Gynecol Oncol 151:525-532
Li, Jiayang; Gresham, Kenneth S; Mamidi, Ranganath et al. (2018) Sarcomere-based genetic enhancement of systolic cardiac function in a murine model of dilated cardiomyopathy. Int J Cardiol 273:168-176
Enane, Francis O; Saunthararajah, Yogen; Korc, Murray (2018) Differentiation therapy and the mechanisms that terminate cancer cell proliferation without harming normal cells. Cell Death Dis 9:912
Lennon, Donald; Solchaga, Luis A; Somoza, Rodrigo A et al. (2018) Human and Rat Bone Marrow-Derived Mesenchymal Stem Cells Differ in Their Response to Fibroblast Growth Factor and Platelet-Derived Growth Factor. Tissue Eng Part A 24:1831-1843
Evans, Daniel R; Venkitachalam, Srividya; Revoredo, Leslie et al. (2018) Evidence for GALNT12 as a moderate penetrance gene for colorectal cancer. Hum Mutat 39:1092-1101
Augestad, Knut M; Keller, Deborah S; Bakaki, Paul M et al. (2018) The impact of rectal cancer tumor height on recurrence rates and metastatic location: A competing risk analysis of a national database. Cancer Epidemiol 53:56-64
Chen, Lechuang; Feng, Zhimin; Yue, Hong et al. (2018) Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA. Nat Commun 9:4585
Patel, Rutulkumar; Zhang, Luchang; Desai, Amar et al. (2018) Mlh1 deficiency increases the risk of hematopoietic malignancy after simulated space radiation exposure. Leukemia :
Lager, Angela M; Corradin, Olivia G; Cregg, Jared M et al. (2018) Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells. Nat Commun 9:3708

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