The Cold Spring Harbor Laboratory Cancer Center is led by Dr. Bruce Stillman, Dr. Scott Lowe and Dr. Nicholas Tonks. Dr, Stillman has been the Director of the CSHL Cancer Center since 1992. As Director of the Cancer Center, he is responsible for overall direction, strategic planning and raising funds to support the research and Shared Resources. He is assisted in oversight of the Cancer Center by two Deputy Directors, Dr. Scott Lowe and Dr. Nicholas Tonks. Dr. Lowe was appointed Deputy Director for Research of the Cancer Center in 2001. In this position, he is primarily responsible for oversight of the cancer research and programs, strategic planning and recruitment of new members to the Cancer Center. Dr. Nicholas Tonks was appointed Deputy Director for Shared Resources for the Cancer Center in 2007. He supervises all the Shared Resource leaders, provides leadership on funding and is responsible for ongoing periodic Shared Resource review. These three senior leaders are committed to maintaining and improving CSHL as a premier center for cancer research.

Public Health Relevance

The Director and Deputy Directors of the Cold Spring Harbor Laboratory Cancer Center oversee a dynamic and vibrant cancer research program and provide leadership for 32 scientists in three research programs who are committed to understanding the underlying mechanisms of cancer as a means to developing strategies for therapeutic intervention.

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National Cancer Institute (NCI)
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Cold Spring Harbor Laboratory
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Chaudhary, Fauzia; Lucito, Robert; Tonks, Nicholas K (2015) Missing-in-Metastasis regulates cell motility and invasion via PTP?-mediated changes in SRC activity. Biochem J 465:89-101
Fan, Gaofeng; Wrzeszczynski, Kazimierz O; Fu, Cexiong et al. (2015) A quantitative proteomics-based signature of platinum sensitivity in ovarian cancer cell lines. Biochem J 465:433-42
Streppel, M M; Lata, S; DelaBastide, M et al. (2014) Next-generation sequencing of endoscopic biopsies identifies ARID1A as a tumor-suppressor gene in Barrett's esophagus. Oncogene 33:347-57
Jensen, Mads A; Wilkinson, John E; Krainer, Adrian R (2014) Splicing factor SRSF6 promotes hyperplasia of sensitized skin. Nat Struct Mol Biol 21:189-97
Chio, Iok In Christine; Yordanov, Georgi; Tuveson, David (2014) MAX-ing out MYC: a novel small molecule inhibitor against MYC-dependent tumors. J Natl Cancer Inst 106:
Eckersley-Maslin, MĂ©lanie A; Thybert, David; Bergmann, Jan H et al. (2014) Random monoallelic gene expression increases upon embryonic stem cell differentiation. Dev Cell 28:351-65
Schwertassek, Ulla; Haque, Aftabul; Krishnan, Navasona et al. (2014) Reactivation of oxidized PTP1B and PTEN by thioredoxin 1. FEBS J 281:3545-58
Yang, Ming; Haase, Astrid D; Huang, Fang-Ke et al. (2014) Dephosphorylation of tyrosine 393 in argonaute 2 by protein tyrosine phosphatase 1B regulates gene silencing in oncogenic RAS-induced senescence. Mol Cell 55:782-90
Bergmann, Jan H; Spector, David L (2014) Long non-coding RNAs: modulators of nuclear structure and function. Curr Opin Cell Biol 26:10-8
Miething, Cornelius; Scuoppo, Claudio; Bosbach, Benedikt et al. (2014) PTEN action in leukaemia dictated by the tissue microenvironment. Nature 510:402-6

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