The UCCC proposes three research Staff Investigators with particular focus in three strategic areas of UCCC development?metastasis and tumor-host microenvironment, cancer stem cell and regenerative medicine, and cancer survivorship. Each Staff Investigator will be responsible for overseeing the coordination, integration and development of research activities in their respective areas across the six Research Programs. Virginia Borges, MD, will serve in the role of Staff Investigator for metastasis and tumor-host microenvironment. She will be responsible for promoting the theme of tumor-host microenvironment interactions and how these affect tumor progression with a specific focus on metastasis across the programs, with the goal of building scientific collaborations to facilitate the development of a new Metastasis and Tumor Microenvironment (MTM) Program. Her research provides a paradigm and model of how immunologic and inflammatory cells promote metastasis, and as a practicing oncologist, she has the knowledge, experience and track record to take these findings to the clinic. Stephen Hunger, MD, will serve in the role of Staff Investigator for cancer stem cell and regenerative medicine. He will be responsible for promoting hematologic oncology research themes including transplantation and stem cell therapy across the programs, with an emphasis on building scientific collaborations to facilitate the development of a new Cancer Stem Cell Program. Dr. Hunger Is an internationally recognized leader in translational research and clinical trials related to childhood acute lymphoblastic leukemia (ALL), with over 100 peer-reviewed publications. Jean Kutner, MD will serve in the role of Staff Investigator for cancer survivorship and palliative care. She will be responsible for promoting survivorship and palliative care research themes across the programs, with an emphasis on building scientific collaborations to facilitate the development of a new Cancer Survivorship Program in the upcoming funding period. Her research in cancer survivorship issues, including late effects and palliative care, provides the appropriate background to oversee the efforts to develop a new survivorship program within the UCCC.
Research Staff Investigators (SI) are important contributors to the programmatic and translational activities of the Cancer Center. The UCCC has 3 Si's in cancer immunology, pediatric oncology/stem cells and cancer survivorship to promote those research themes across the scientific programs and advance the development of new programs in the areas of Cancer Stem Cells, Metastasis and Tumor Microenvironment, and Cancer Survivorship.
|Finlay-Schultz, J; Cittelly, D M; Hendricks, P et al. (2015) Progesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and Stat5a. Oncogene 34:3676-87|
|Alvarez-Calderon, Francesca; Gregory, Mark A; Pham-Danis, Catherine et al. (2015) Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations. Clin Cancer Res 21:1360-72|
|Roth, Lauren W; Bradshaw-Pierce, Erica L; Allshouse, Amanda A et al. (2014) Evidence of GnRH antagonist escape in obese women. J Clin Endocrinol Metab 99:E871-5|
|Kumar, Sushil; Raina, Komal; Agarwal, Chapla et al. (2014) Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals. Oncotarget 5:4972-89|
|Roth, Lauren W; Allshouse, Amanda A; Bradshaw-Pierce, Erica L et al. (2014) Luteal phase dynamics of follicle-stimulating and luteinizing hormones in obese and normal weight women. Clin Endocrinol (Oxf) 81:418-25|
|Colussi, Timothy M; Costantino, David A; Hammond, John A et al. (2014) The structural basis of transfer RNA mimicry and conformational plasticity by a viral RNA. Nature 511:366-9|
|Griesinger, Andrea M; Donson, Andrew M; Foreman, Nicholas K (2014) Immunotherapeutic implications of the immunophenotype of pediatric brain tumors. Oncoimmunology 3:e27256|
|Marek, Lindsay A; Hinz, Trista K; von Mässenhausen, Anne et al. (2014) Nonamplified FGFR1 is a growth driver in malignant pleural mesothelioma. Mol Cancer Res 12:1460-9|
|Holliday, Michael J; Zhang, Fengli; Isern, Nancy G et al. (2014) 1H, 13C, and 15N backbone and side chain resonance assignments of thermophilic Geobacillus kaustophilus cyclophilin-A. Biomol NMR Assign 8:23-7|
|Milgroom, Andrew; Intrator, Miranda; Madhavan, Krishna et al. (2014) Mesoporous silica nanoparticles as a breast-cancer targeting ultrasound contrast agent. Colloids Surf B Biointerfaces 116:652-7|
Showing the most recent 10 out of 678 publications