PLANNING AND EVALUATION (Core-453) ABSTRACT Overview: The University of Colorado Cancer Center's (UCCC) Planning and Evaluation (P&E) activities, under the leadership of Dan Theodorescu MD PhD, are focused on the comprehensive strategic review of the UCCC and its Research Programs, Shared Resources (SRs), Clinical Research, and associated operations to ensure the optimization of UCCC's activities and the recognition and pursuit of particular opportunities. The P&E component is conducted in a multi-faceted approach that includes the review and assessment by the External Advisory Board (EAB), several key internal advisory committees, and the Senior Leadership of the UCCC. These activities are augmented by specific ad hoc individual and group external reviewers along with key input from UCCC members through UCCC organizational structures. Following the NCI Site Visit of the UCCC in June 2011 and receipt of the detailed CCSG review, UCCC Senior Leadership and Research Program Leaders initiated a series of meetings to identify key areas for development and recruitment in addition to those strategic directions outlined in the Director's Overview. Key areas were identified as recruitment of an Associate Director for Population Sciences Research, the reconstruction of the Protocol Review and Monitoring System (PRMS) which had been disapproved and implementation of better educational opportunities and infrastructure (new clinical trial management system (CTMS)) in support of clinical investigation. The UCCC External Advisory Board (EAB) played a critical role in this strategic planning and evaluation activities through annual visits and written feedback. Accomplishments: Since 2011 such P&E activities have led to the successful accomplishments of many of the strategic directions outlined in the Director's Overview in addition to the key areas outlined above. In the next funding period, the P&E component proposes the following Specific Aims: 1) Creation of appropriate external and internal advisory bodies to ensure strategic development, expert guidance, and rigorous review of UCCC research programs and activities; and 2) Development of processes for continuous review and improvement of UCCC programs to ensure efficiency, effectiveness, and concordance with UCCC strategic initiatives.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA046934-30
Application #
9429046
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2018-02-01
Budget End
2019-01-31
Support Year
30
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Type
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Greer, Robert O; Eskendri, Jeffrey; Freedman, Paul et al. (2018) Assessment of biologically aggressive, recurrent glandular odontogenic cysts for mastermind-like 2 (MAML2) rearrangements: histopathologic and fluorescent in situ hybridization (FISH) findings in 11 cases. J Oral Pathol Med 47:192-197
Tippimanchai, Darinee D; Nolan, Kyle; Poczobutt, Joanna et al. (2018) Adenoviral vectors transduce alveolar macrophages in lung cancer models. Oncoimmunology 7:e1438105
Ravindran Menon, Dinoop; Luo, Yuchun; Arcaroli, John J et al. (2018) CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma. Cancer Res 78:6561-6574
Genova, Carlo; Socinski, Mark A; Hozak, Rebecca R et al. (2018) EGFR Gene Copy Number by FISH May Predict Outcome of Necitumumab in Squamous Lung Carcinomas: Analysis from the SQUIRE Study. J Thorac Oncol 13:228-236
Galati, Domenico F; Sullivan, Kelly D; Pham, Andrew T et al. (2018) Trisomy 21 Represses Cilia Formation and Function. Dev Cell 46:641-650.e6
Gavin, Kathleen M; Sullivan, Timothy M; Kohrt, Wendy M et al. (2018) Ovarian Hormones Regulate the Production of Adipocytes From Bone Marrow-Derived Cells. Front Endocrinol (Lausanne) 9:276
Nichols, Parker J; Henen, Morkos A; Born, Alexandra et al. (2018) High-resolution small RNA structures from exact nuclear Overhauser enhancement measurements without additional restraints. Commun Biol 1:61
Libby, Andrew E; Bales, Elise S; Monks, Jenifer et al. (2018) Perilipin-2 deletion promotes carbohydrate-mediated browning of white adipose tissue at ambient temperature. J Lipid Res 59:1482-1500
Hintzsche, Jennifer D; Yoo, Minjae; Kim, Jihye et al. (2018) IMPACT web portal: oncology database integrating molecular profiles with actionable therapeutics. BMC Med Genomics 11:26
Cao, Shengya; Zhou, Keda; Zhang, Zhening et al. (2018) Constitutive centromere-associated network contacts confer differential stability on CENP-A nucleosomes in vitro and in the cell. Mol Biol Cell 29:751-762

Showing the most recent 10 out of 1634 publications