The mission of the Georgetown Lombardi Comprehensive Cancer Center's (LCCC) Administration is to facilitate and implement LCCC's vision and create, support, and sustain an environment that fosters research, interactivity, and optimal productivity of Cancer Center investigators and adds value to the Center. Supporting 4 Research Programs, 9 Shared Resources and 91 members focused on basic, translational, clinical, and population-based research, Administration oversees $30M in grants and contracts (direct costs). Headed by Michael Vander Hoek, MHSA, Associate Director (AD) for Administration, the administrative team supports LCCC leadership planning, strategic investments, benchmarking and evaluation, and communication with constituencies. In addition to building an experienced management team to support Cancer Center members, Vander Hoek managed the recruitment of several key LCCC leaders including the Deputy Director, AD for Clinical Research, and the Codirector of the Biostatistics &Bioinformatics Shared Resource (SR) and supported the faculty appointments and promotions of several SR Directors and Research Program members. He and his team have successfully managed institutional commitments to support these strategic initiatives. Administration tracks and manages LCCC's $25M per year in institutional investments from the University and MedStar Health, ensuring investments are linked to LCCC's Strategic Plan. Administration documents and executes LCCC policies on membership, pilot funding, equipment purchases. Shared Resources and space. During this period. Administration supported opening a community office for health disparities research in one of the most underserved areas ofthe District of Columbia. Cancer research education and training are also coordinated by Administration. Significant expansion of administrative activities have supported an increasingly productive relationship with our MedStar Health clinical partner in strengthening a clinical network aimed at increasing accrual to therapeutic trials and increasing the diversity of individuals enrolling on trials. For example. Administration negotiated a research agreement to expand and strengthen the clinical research organizational structure across the Georgetown MedStar Cancer Network creating an integrated Clinical Research Management Office (ICRMO). Other activities are highlighted within the narrative. The CCSG budget requested represents 6.6% of the total LCCC administrative budget and represents 7.6% ofthe total CCSG budget.

Public Health Relevance

Lombardi Administration advances the vision of Cancer Center leaders in a thriving environment that supports, evaluates and sustains research activities that are innovative, transformative, collaborative and well organized.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Georgetown University
United States
Zip Code
Smith, Jill P; Wang, Shangzi; Nadella, Sandeep et al. (2017) Cholecystokinin receptor antagonist alters pancreatic cancer microenvironment and increases efficacy of immune checkpoint antibody therapy in mice. Cancer Immunol Immunother :
Rao, Guanhua; Pierobon, Mariaelena; Kim, In-Kyu et al. (2017) Inhibition of AKT1 signaling promotes invasion and metastasis of non-small cell lung cancer cells with K-RAS or EGFR mutations. Sci Rep 7:7066
Lynce, Filipa; Barac, Ana; Tan, Ming T et al. (2017) SAFE-HEaRt: Rationale and Design of a Pilot Study Investigating Cardiac Safety of HER2 Targeted Therapy in Patients with HER2-Positive Breast Cancer and Reduced Left Ventricular Function. Oncologist 22:518-525
Vietsch, Eveline E; Graham, Garrett T; McCutcheon, Justine N et al. (2017) Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer. Cancer Genet 218-219:39-50
Walker, Logan C; Marquart, Louise; Pearson, John F et al. (2017) Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers. Eur J Hum Genet 25:432-438
Zhang, Yong-Wei; Nasto, Rochelle E; Jablonski, Sandra A et al. (2017) RNA Interference Screening to Identify Proliferation Determinants in Breast Cancer Cells. Bio Protoc 7:
DeVito, Stephen; Woodrick, Jordan; Song, Linze et al. (2017) Mutagenic potential of hypoxanthine in live human cells. Mutat Res 803-805:9-16
Wang, Hongkun; Wang, Ying; Kota, Krishna K et al. (2017) Strong associations between chromosomal aberrations in blood lymphocytes and the risk of urothelial and squamous cell carcinoma of the bladder. Sci Rep 7:13493
Parodi, Daniela A; Greenfield, Morgan; Evans, Claire et al. (2017) Alteration of Mammary Gland Development and Gene Expression by In Utero Exposure to Cadmium. Int J Mol Sci 18:
Casero, David; Gill, Kirandeep; Sridharan, Vijayalakshmi et al. (2017) Space-type radiation induces multimodal responses in the mouse gut microbiome and metabolome. Microbiome 5:105

Showing the most recent 10 out of 997 publications