Overview and Response to Previous Review The Robert H. Lurie Comprehensive Cancer Center of Northwestern University (Lurie Cancer Center) is dedicated to the conduct of innovative, translational clinical research. Novel investigator-initiated clinical trials (IITs) are a key element ofthe Lurie Cancer Center clinical research program and are of highest priority. In this competitive granting environment, funding for such studies is often either unavailable or only partially available. While industry sponsors are an important source of funds for such trials, the start-up process with our industry partners can be lengthy. The work of the Operational Efficiency Working Group (OEWG) has made it clear that rapid activation and enrollment to trials is vital. As such, the Lurie Cancer Center is committed to facilitating local, IITs through the CCSG mechanism of Protocol Specific Research Support (PSRS). PSRS funding is competitive in nature and supports protocol coordination and data management for early phase research trials. The goal of such support is to allow for the rapid development and completion of novel, translational hypothesis-driven trials that show promise for advancement to later phase clinical research deserving of independent funding. IITs are those institutional trials that are conceived of and written by Lurie Cancer Center investigators, and fall under the purview ofthe Lurie Cancer Center for ensuring appropriate conduct ofthe trial. Since the last competing application, the Lurie Cancer Center has provided support to 21 trials developed by Lurie Cancer Center members. The funding request for PSRS in this competing application consists of one Study Coordinator and one Data Manager.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA060553-19
Application #
8588663
Study Section
Subcommittee G - Education (NCI)
Project Start
1997-08-01
Project End
2018-07-31
Budget Start
2013-09-16
Budget End
2014-07-31
Support Year
19
Fiscal Year
2013
Total Cost
$175,149
Indirect Cost
$61,832
Name
Northwestern University at Chicago
Department
Type
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Zhao, J C; Fong, K-W; Jin, H-J et al. (2016) FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression. Oncogene 35:4335-44
Kaluzny, Joel; Purta, Patryk; Poskin, Zach et al. (2016) Ex Vivo Confocal Spectroscopy of Autofluorescence in Age-Related Macular Degeneration. PLoS One 11:e0162869
Marsh, Erica E; Chibber, Shani; Wu, Ju et al. (2016) Epidermal growth factor-containing fibulin-like extracellular matrix protein 1 expression and regulation in uterine leiomyoma. Fertil Steril 105:1070-5
Zhao, Baobing; Mei, Yang; Schipma, Matthew J et al. (2016) Nuclear Condensation during Mouse Erythropoiesis Requires Caspase-3-Mediated Nuclear Opening. Dev Cell 36:498-510
Ridge, Karen M; Shumaker, Dale; Robert, Amélie et al. (2016) Methods for Determining the Cellular Functions of Vimentin Intermediate Filaments. Methods Enzymol 568:389-426
White, Sarah Beth; Procissi, Daniele; Chen, Jeane et al. (2016) Characterization of CC-531 as a Rat Model of Colorectal Liver Metastases. PLoS One 11:e0155334
Cohee, Andrea A; Stump, Timothy; Adams, Rebecca N et al. (2016) Factors associated with depressive symptoms in young long-term breast cancer survivors. Qual Life Res 25:1991-7
Isabella, Adam J; Horne-Badovinac, Sally (2016) Rab10-Mediated Secretion Synergizes with Tissue Movement to Build a Polarized Basement Membrane Architecture for Organ Morphogenesis. Dev Cell 38:47-60
Valdovinos, Cristina; Penedo, Frank J; Isasi, Carmen R et al. (2016) Perceived discrimination and cancer screening behaviors in US Hispanics: the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study. Cancer Causes Control 27:27-37
Quinn, Gwendolyn P; Woodruff, Teresa K; Knapp, Caprice A et al. (2016) Expanding the Oncofertility Workforce: Training Allied Health Professionals to Improve Health Outcomes for Adolescents and Young Adults. J Adolesc Young Adult Oncol 5:292-6

Showing the most recent 10 out of 1027 publications