The Robert H. Lurie Comprehensive Cancer Center of Northwestern University is an NCI-designated, university based, matrix cancer center conducting a broad range of multidisciplinary clinical, laboratory and population science research. The Lurie Cancer Center integrates the expertise and resources of the Feinberg School of Medicine (Chicago Campus) and its affiliated hospitals along with those of departments located on the University's Evanston Campus. Established in 1974, the Lurie Cancer Center functions as a full organizational unit with the status of a department of the Feinberg School of Medicine. Since its inception, the Lurie Cancer Center has been dedicated to the process of discovery, advancing medical knowledge and providing compassionate, state-of-the-art cancer care, and conducting community outreach and survivorship programs as reflected in the following goals: 1. To conduct and support cancer research and to integrate cancer-related research throughout the University;2. To coordinate and integrate cancer-related activities of the University including community outreach initiatives;3. To develop and conduct cancer education programs;4. To promote and participate in state-of-the-art care of cancer patients at the affiliated hospitals, and 5. To develop and implement initiatives in cancer prevention and control research. These goals are accomplished through the activities of 9 established programs and 15 shared resources. Programs: 1. Cancer Cell Biology; 2. Tumor Invasion, Metastasis, &Angiogenesis; 3. Signal Transduction in Cancer;4. Cancer and Physical Sciences;5. Women's Cancer;6. Translational Research in Solid Tumors;7. Hematologic Malignancies;8. Cancer Prevention;and 9. Cancer Control and Survivorship. Shared Resources: 1. Cell Imaging;2. Developmental Therapeutics;3. Flow Cytometry;4. High Throughput; 5. Keck Biophysics;6. Medicinal &Synthetic Chemistry Core; 7. Molecular &Translational Imaging; 8. Mouse Phenotyping; 9. Pathology Core;10. Structural Biology;11. Transgenic and Targeted Mutagenesis Laboratory;12. Outcomes Measurement &Survey Core;13. Cancer Informatics;14. Biostatistics;and 15. Clinical Research Office. This competing renewal application is being submitted as a Consortium/Partnership Application including the main institution and Ann &Robert H. Lurie Children's Hospital of Chicago. Cancer Center members at the partner institution are fully integrated with those at the main campuses of the University and together contribute to the ongoing progress of the Center in achieving its mission, goals and objectives. This Cancer Center Support Grant is requested to provide support for the critical infrastructure and shared resources needed by our scientific program investigators to seek methods for the prevention, diagnosis, treatment and rehabilitation of cancer.

Public Health Relevance

This Cancer Center Support Grant is requested to provide support for the critical infrastructure and shared resources needed by our scientific program investigators to seek methods forthe prevention, diagnosis, treatment and rehabilitation of cancer.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA060553-19S1
Application #
8709077
Study Section
Subcommittee G - Education (NCI)
Program Officer
Ptak, Krzysztof
Project Start
1997-08-01
Project End
2015-07-31
Budget Start
2013-09-17
Budget End
2014-07-31
Support Year
19
Fiscal Year
2013
Total Cost
$75,000
Indirect Cost
$26,456
Name
Northwestern University at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Ogasawara, Noriko; Poposki, Julie A; Klingler, Aiko I et al. (2018) IL-10, TGF-?, and glucocorticoid prevent the production of type 2 cytokines in human group 2 innate lymphoid cells. J Allergy Clin Immunol 141:1147-1151.e8
Fisher, Oriana S; Kenney, Grace E; Ross, Matthew O et al. (2018) Characterization of a long overlooked copper protein from methane- and ammonia-oxidizing bacteria. Nat Commun 9:4276
Lin, Hsin-Pin; Oksuz, Idil; Svaren, John et al. (2018) Egr2-dependent microRNA-138 is dispensable for peripheral nerve myelination. Sci Rep 8:3817
Nguyen, Maria; Krainc, Dimitri (2018) LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson's disease. Proc Natl Acad Sci U S A 115:5576-5581
Ritzert, Jeremy T; Lathem, Wyndham W (2018) Depletion of Glucose Activates Catabolite Repression during Pneumonic Plague. J Bacteriol 200:
Bui, Triet M; Mascarenhas, Lorraine A; Sumagin, Ronen (2018) Extracellular vesicles regulate immune responses and cellular function in intestinal inflammation and repair. Tissue Barriers 6:e1431038
Park, Yun Ji; Kenney, Grace E; Schachner, Luis F et al. (2018) Repurposed HisC Aminotransferases Complete the Biosynthesis of Some Methanobactins. Biochemistry 57:3515-3523
Forte, Eleonora; Swaminathan, Suchitra; Schroeder, Mark W et al. (2018) Tumor Necrosis Factor Alpha Induces Reactivation of Human Cytomegalovirus Independently of Myeloid Cell Differentiation following Posttranscriptional Establishment of Latency. MBio 9:
Mandelin 2nd, Arthur M; Homan, Philip J; Shaffer, Alexander M et al. (2018) Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis. Arthritis Rheumatol 70:841-854
Fong, Lam-Kiu; Wang, Ziwei; Schatz, George C et al. (2018) The Role of Structural Enthalpy in Spherical Nucleic Acid Hybridization. J Am Chem Soc 140:6226-6230

Showing the most recent 10 out of 1972 publications