Staff Investigators will oversee the conduct of the Translational Pilot Project Working Groups in the five identified disease site for this cycle, which are 1) Breast, 2) Cervix, 3) Gl, 4) Melanoma, and 5) Prostate.
Aims and Purpose To identify and prioritize the most pressing problems facing medical research today, as disease site and/or discipline applicable, that can be uniquely addressed and facilitated by the CFCCC o Outcome invest efforts in emerging and needed areas of research and patient care To develop research teams of the future that support both individual creativity and collaborative team efforts by facilitating interdisciplinary research, high-risk research, patient care, and public-private partnerships o Outcome boost resources and technologies needed for 21st century biomedical science and patient care To facilitate the translation of basic, clinical and epidemiologic findings into hypothesis-driven UCIinvestigator initiated diagnostic, preventive, and therapeutic or cancer survivorship intervention trials at the individual or population level o Outcome translational bench to bedside research, diagnostic prevention, and treatment clinical protocols involving a collaboration of Members

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA062203-17S2
Application #
8567227
Study Section
Subcommittee G - Education (NCI)
Project Start
1997-09-11
Project End
2014-01-31
Budget Start
2012-02-01
Budget End
2013-01-31
Support Year
17
Fiscal Year
2012
Total Cost
$49,998
Indirect Cost
$17,443
Name
University of California Irvine
Department
Type
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92697
Wang, Yajun; Ngor, Arlene K; Nikoomanzar, Ali et al. (2018) Evolution of a General RNA-Cleaving FANA Enzyme. Nat Commun 9:5067
Qiu, Xiaolong; Lombardo, Jeremy A; Westerhof, Trisha M et al. (2018) Microfluidic filter device with nylon mesh membranes efficiently dissociates cell aggregates and digested tissue into single cells. Lab Chip 18:2776-2786
Patterson, Kurt; Yu, James; Landberg, Jenny et al. (2018) Functional genomics for the oleaginous yeast Yarrowia lipolytica. Metab Eng 48:184-196
Lee, J Scott; Roberts, Andrew; Juarez, Dennis et al. (2018) Statins enhance efficacy of venetoclax in blood cancers. Sci Transl Med 10:
Sierra, Robert A; Hoverter, Nathan P; Ramirez, Ricardo N et al. (2018) TCF7L1 suppresses primitive streak gene expression to support human embryonic stem cell pluripotency. Development 145:
Maciejewski, Sonia; Ullmer, Wendy; Semler, Bert L (2018) VPg unlinkase/TDP2 in cardiovirus infected cells: Re-localization and proteolytic cleavage. Virology 516:139-146
Konstorum, Anna; Lowengrub, John S (2018) Activation of the HGF/c-Met axis in the tumor microenvironment: A multispecies model. J Theor Biol 439:86-99
Yan, Huaming; Konstorum, Anna; Lowengrub, John S (2018) Three-Dimensional Spatiotemporal Modeling of Colon Cancer Organoids Reveals that Multimodal Control of Stem Cell Self-Renewal is a Critical Determinant of Size and Shape in Early Stages of Tumor Growth. Bull Math Biol 80:1404-1433
Wang, Xiaolin; Zhao, Da; Phan, Duc T T et al. (2018) A hydrostatic pressure-driven passive micropump enhanced with siphon-based autofill function. Lab Chip 18:2167-2177
Flather, Dylan; Nguyen, Joseph H C; Semler, Bert L et al. (2018) Exploitation of nuclear functions by human rhinovirus, a cytoplasmic RNA virus. PLoS Pathog 14:e1007277

Showing the most recent 10 out of 1106 publications