The Vanderbilt-lngram Cancer Center (VICC) employs both internal and external review mechanisms to inform and support the strategic decisions made by the center and to provide feedback necessary for ongoing evaluation of the effectiveness of those decisions. Program Planning and Evaluation provides a structured approach for assessing our current status relative to strategic planning, identifying opportunities and formulating approaches for implementing the mission of the VICC. These processes ensure effective and well-coordinated use of Cancer Center Support Grant (CCSG) resources, institutional discretionary support and philanthropic funds. The significant progress of the VICC, described throughout this renewal application, continues to provide evidence in support of the effective use of both internal and external planning and evaluation processes. The Director has the ultimate responsibility and authority for setting priorities for the development of new research programs and shared resources;recruiting and retaining scientists and scientific leaders;selecting programs, projects and individuals to receive seed grant funding; determining use of VICC space and resources;and organizing the Center as a whole to promote scientific interactions and enhance productivity. To ensure the Director receives the best advice possible, she relies on several committees for identifying short- and long-term initiatives, implementing policies, evaluating processes and participating in decision-making activities. These working groups help manage Center affairs as well as provide the setting for the Senior Leaders to exchange ideas with Program Leaders, Shared Resource Managers, and External Advisors. Internal groups include the Executive Committee, Research Program Leaders Committee, Shared Resource Oversight Group, Minority Affairs and Health Disparities Taskforce, Translational and Therapeutic Taskforce Committee, Cancer Clinical Enterprise Committee and the Clinical Enterprise Executive Committee. Two external groups provide opportunities for comprehensive planning and evaluation processes within the VICC, the External Scientific Advisory Board and the Board of Overseers.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA068485-18
Application #
8733533
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
18
Fiscal Year
2014
Total Cost
$118,578
Indirect Cost
$89,304
Name
Vanderbilt University Medical Center
Department
Type
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Han, Ying; Signorello, Lisa B; Strom, Sara S et al. (2015) Generalizability of established prostate cancer risk variants in men of African ancestry. Int J Cancer 136:1210-7
Sanders, Melinda E; Schuyler, Peggy A; Simpson, Jean F et al. (2015) Continued observation of the natural history of low-grade ductal carcinoma in situ reaffirms proclivity for local recurrence even after more than 30 years of follow-up. Mod Pathol 28:662-9
Chaturvedi, R; de Sablet, T; Asim, M et al. (2015) Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase. Oncogene 34:3429-40
Vilgelm, Anna E; Pawlikowski, Jeff S; Liu, Yan et al. (2015) Mdm2 and aurora kinase a inhibitors synergize to block melanoma growth by driving apoptosis and immune clearance of tumor cells. Cancer Res 75:181-93
Wei, Jinxiong; Noto, Jennifer M; Zaika, Elena et al. (2015) Bacterial CagA protein induces degradation of p53 protein in a p14ARF-dependent manner. Gut 64:1040-8
Carrillo, A M; Bouska, A; Arrate, M P et al. (2015) Mdmx promotes genomic instability independent of p53 and Mdm2. Oncogene 34:846-56
Balko, Justin M; Giltnane, Jennifer M; Wang, Kai et al. (2014) Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets. Cancer Discov 4:232-45
Weeke, Peter; Mosley, Jonathan D; Hanna, David et al. (2014) Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome. J Am Coll Cardiol 63:1430-7
Cheng, Feixiong; Jia, Peilin; Wang, Quan et al. (2014) Studying tumorigenesis through network evolution and somatic mutational perturbations in the cancer interactome. Mol Biol Evol 31:2156-69
Peng, Dun-Fa; Hu, Tian-Ling; Soutto, Mohammed et al. (2014) Loss of glutathione peroxidase 7 promotes TNF-?-induced NF-?B activation in Barrett's carcinogenesis. Carcinogenesis 35:1620-8

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