The Cancer Research Center of Hawaii (CRCH) is an NCI-designated Clinical Cancer Center. CRCH has diverse responsibility in cancer research, education, community outreach, and patient care. It is the only such institution in the State of Hawaii. Hawaii offers special research opportunities for cancer that are unparalleled elsewhere in the country or the world. The basis for the unique research opportunities in Hawaii are the ethnic and cultural variety of the State's population as well as its geographic location and unique environment. Research efforts at CRCH are organized into three research programs: Cancer Etiology, Prevention and Control, and Natural Products and Cancer Biology. All three research programs take particular advantage of the biodiversity offered by the multiethnic population of Hawaii for basic, population-based, and clinical studies as well as by the natural diversity of the tropical biosphere for drug discovery. All three programs have made significant scientific progress during the current CCSG funding cycle. Exciting and novel research results have been obtained and disseminated in over 800 publications in the international literature from 1999 until today. CRCH also operates the Hawaii Tumor Registry, one of 12 SEER registries in the country, the Cancer Information Service-Pacific, and a large Clinical Trials Unit which makes approximately 150 clinical trials available to Hawaii's cancer patients. Over the current cycle of CCSG support research space at CRCH approximately doubled, including approximately 50,000 square feet in a new research building to be completed by mid-2005. Furthermore, plans are underway to construct a new Cancer Center building of approximately 350,000 square feet which will not only provide expanded facilities for current research programs, but will include a modern outpatient care facility offering comprehensive cancer care services in partnership with the largest hospitals in the State. These developments will allow to build a strong clinical research activity in the future.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA071789-12S9
Application #
8138676
Study Section
Subcommittee G - Education (NCI)
Program Officer
Shafik, Hasnaa
Project Start
1997-07-01
Project End
2012-06-30
Budget Start
2008-08-25
Budget End
2012-06-30
Support Year
12
Fiscal Year
2011
Total Cost
$720,185
Indirect Cost
Name
University of Hawaii
Department
Type
Organized Research Units
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Guo, Zhenying; Carbone, Michele; Zhang, Xing et al. (2017) Improving the Accuracy of Mesothelioma Diagnosis in China. J Thorac Oncol 12:714-723
Furuya, Hideki; Shimizu, Yoshiko; Tamashiro, Paulette M et al. (2017) Sphingosine kinase 1 expression enhances colon tumor growth. J Transl Med 15:120
Xie, Guoxiang; Wang, Xiaoning; Zhao, Aihua et al. (2017) Sex-dependent effects on gut microbiota regulate hepatic carcinogenic outcomes. Sci Rep 7:45232
Lloyd, Yukie M; Ngati, Elise P; Salanti, Ali et al. (2017) A versatile, high through-put, bead-based phagocytosis assay for Plasmodium falciparum. Sci Rep 7:14705
Park, Sungshim L; Murphy, Sharon E; Wilkens, Lynne R et al. (2017) Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study. PLoS One 12:e0178435
Conroy, Shannon M; Clarke, Christina A; Yang, Juan et al. (2017) Contextual Impact of Neighborhood Obesogenic Factors on Postmenopausal Breast Cancer: The Multiethnic Cohort. Cancer Epidemiol Biomarkers Prev 26:480-489
Huang, Madelyn C; Douillet, Christelle; Su, Mingming et al. (2017) Metabolomic profiles of arsenic (+3 oxidation state) methyltransferase knockout mice: effect of sex and arsenic exposure. Arch Toxicol 91:189-202
Boushey, Carol J; Spoden, Melissa; Delp, Edward J et al. (2017) Reported Energy Intake Accuracy Compared to Doubly Labeled Water and Usability of the Mobile Food Record among Community Dwelling Adults. Nutrients 9:
Mao, Weimin; Zhang, Xing; Guo, Zhenying et al. (2017) Association of Asbestos Exposure With Malignant Mesothelioma Incidence in Eastern China. JAMA Oncol 3:562-564
Harmon, Brook E; Wirth, Michael D; Boushey, Carol J et al. (2017) The Dietary Inflammatory Index Is Associated with Colorectal Cancer Risk in the Multiethnic Cohort. J Nutr 147:430-438

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