The Biostatistics and Informatics Shared Resource (BISR) plays an essential role in the research activities of the University of Hawai'i Cancer Center. The biostatistics function, established in 1995, and the informatics function, established in 2004, have recently been consolidated in order to provide a seamless support system to Cancer Center members. The formation of a cohesive group of statisticians and informaticians helps assure uniform excellence in all aspects of data management and analysis across all projects and allows for an exchange of methodological approaches leading to more efficient and creative solutions. The overarching goal of the BISR is to ensure that sound analytic principles are followed, thereby improving the quality of the research enterprise of the Cancer Center. Eighteen members and 14.82 FTE are currently included in the Biostatistics and Informatics Shared Resource. Services provided include consultation on study design, data collection, data management, data analysis, statistical programming, bioinformatics and systems biology, interpretation of findings, and clinical trials protocol support. During the last cycle of the CCSG grant, members of the resource contributed to 199 publications, including 155 as co-authors, served as co-investigators on 75 single project grants and 2 multi-project grants, and contributed to the submission of 90 grants, 45 of which were funded. The resource will continue to meet the biostatistical and informatics needs of the University of Hawai'i Cancer Center, will continue to perform methodological research important to the research of cancer center members, and will continue to develop a computational infrastructure for the storage and processing of high-dimensional data.

Public Health Relevance

The Biostatistics and Informatics Shared Resource (BISR) plays an essential role in the research activities of the University of Hawai'i Cancer Center. The resource provides collaboration and support on all aspects of data management and analysis for research projects and builds quantitative capacity center-wide. This consultation is based on sound analytic principles which improves the quality of the research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA071789-14
Application #
8565945
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
14
Fiscal Year
2013
Total Cost
$97,385
Indirect Cost
$26,072
Name
University of Hawaii
Department
Type
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Gong, J; Nishimura, K K; Fernandez-Rhodes, L et al. (2018) Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI. Int J Obes (Lond) 42:384-390
Pokhrel, Pallav; Herzog, Thaddeus A; Fagan, Pebbles et al. (2018) E-cigarette Advertising Exposure, Explicit and Implicit Harm Perceptions, and E-Cigarette use Susceptibility Among Non-Smoking Young Adults. Nicotine Tob Res :
Wu, Eric M; Hernandez, Brenda Y; Wong, Linda L (2018) Hepatocellular carcinoma in Micronesians, a growing Pacific Islander population in the U.S. Open J Gastroenterol 8:
Murphy, Sharon E; von Weymarn, Linda B; Parenteau, Marc et al. (2018) Influence of UGT2B10 Genotype on Urinary Excretion of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol- N-glucuronide by African American Smokers. Chem Res Toxicol 31:168-175
Loo, Lenora W M; Williams, Makana; Hernandez, Brenda Y (2018) The high and heterogeneous burden of breast cancer in Hawaii: A unique multiethnic U.S. Population. Cancer Epidemiol 58:71-76
Hernandez, Brenda Y; Tareg, Aileen C; Reichhardt, Martina et al. (2018) Randomized controlled trial evaluating the utility of urine HPV DNA for cervical cancer screening in a Pacific Island population. J Glob Health Rep 2:
Gu, Yuanzhuo; Wei, Xiyang; Sun, Yulin et al. (2018) miR-192-5p silencing by genetic aberrations is a key event in hepatocellular carcinomas with cancer stem cell features. Cancer Res :
Lim, Unhee; Monroe, Kristine R; Buchthal, Steve et al. (2018) Propensity for Intra-abdominal and Hepatic Adiposity Varies Among Ethnic Groups. Gastroenterology :
Maskarinec, Gertraud; Ju, Dan; Fong, Jaimie et al. (2018) Mammographic density and breast tissue expression of inflammatory markers, growth factors, and vimentin. BMC Cancer 18:1191
Amshoff, Yvette; Maskarinec, Gertraud; Shvetsov, Yurii B et al. (2018) Type 2 diabetes and colorectal cancer survival: The multiethnic cohort. Int J Cancer 143:263-268

Showing the most recent 10 out of 562 publications