The Biostatistics and Informatics Shared Resource (BISR) plays an essential role in the research activities of the University of Hawai'i Cancer Center. The biostatistics function, established in 1995, and the informatics function, established in 2004, have recently been consolidated in order to provide a seamless support system to Cancer Center members. The formation of a cohesive group of statisticians and informaticians helps assure uniform excellence in all aspects of data management and analysis across all projects and allows for an exchange of methodological approaches leading to more efficient and creative solutions. The overarching goal of the BISR is to ensure that sound analytic principles are followed, thereby improving the quality of the research enterprise of the Cancer Center. Eighteen members and 14.82 FTE are currently included in the Biostatistics and Informatics Shared Resource. Services provided include consultation on study design, data collection, data management, data analysis, statistical programming, bioinformatics and systems biology, interpretation of findings, and clinical trials protocol support. During the last cycle of the CCSG grant, members of the resource contributed to 199 publications, including 155 as co-authors, served as co-investigators on 75 single project grants and 2 multi-project grants, and contributed to the submission of 90 grants, 45 of which were funded. The resource will continue to meet the biostatistical and informatics needs of the University of Hawai'i Cancer Center, will continue to perform methodological research important to the research of cancer center members, and will continue to develop a computational infrastructure for the storage and processing of high-dimensional data.

Public Health Relevance

The Biostatistics and Informatics Shared Resource (BISR) plays an essential role in the research activities of the University of Hawai'i Cancer Center. The resource provides collaboration and support on all aspects of data management and analysis for research projects and builds quantitative capacity center-wide. This consultation is based on sound analytic principles which improves the quality of the research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA071789-14S1
Application #
8724379
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
14
Fiscal Year
2013
Total Cost
$6,662
Indirect Cost
$2,250
Name
University of Hawaii
Department
Type
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Fagan, Pebbles; Pokhrel, Pallav; Herzog, Thaddeus A et al. (2016) Nicotine Metabolism in Young Adult Daily Menthol and Nonmenthol Smokers. Nicotine Tob Res 18:437-46
Paladino, David; Yue, Peibin; Furuya, Hideki et al. (2016) A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer. Oncotarget 7:7253-67
Rosty, Christophe; Clendenning, Mark; Walsh, Michael D et al. (2016) Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort. BMJ Open 6:e010293
Huang, Sijia; Chong, Nicole; Lewis, Nathan E et al. (2016) Novel personalized pathway-based metabolomics models reveal key metabolic pathways for breast cancer diagnosis. Genome Med 8:34
Kuo, Mei-Ling; Lee, Mabel Bin-Er; Tang, Michelle et al. (2016) PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress. Sci Rep 6:18846
Iwasaki, Motoki; Le Marchand, Loïc; Franke, Adrian A et al. (2016) Comparison of plasma levels of obesity-related biomarkers among Japanese populations in Tokyo, Japan, São Paulo, Brazil, and Hawaii, USA. Eur J Cancer Prev 25:41-9
Giorgi, Elena E; Li, Yuqing; Caberto, Christian P et al. (2016) No Association between the Mitochondrial Genome and Prostate Cancer Risk: The Multiethnic Cohort. Cancer Epidemiol Biomarkers Prev 25:1001-3
Leo, Q J N; Ollberding, N J; Wilkens, L R et al. (2016) Nutritional factors and non-Hodgkin lymphoma survival in an ethnically diverse population: the Multiethnic Cohort. Eur J Clin Nutr 70:41-6
Wu, Kana; Spiegelman, Donna; Hou, Tao et al. (2016) Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies. Int J Cancer 138:2368-82
Setiawan, Veronica Wendy; Wei, Pengxiao C; Hernandez, Brenda Y et al. (2016) Disparity in liver cancer incidence and chronic liver disease mortality by nativity in Hispanics: The Multiethnic Cohort. Cancer 122:1444-52

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