Moffitt proposes 7 staff investigators, each at 10% effort for a total of 8.4 calendar months to serve key leadership roles in the development of focused and translational research, working with the ACD of Translational Research and the other ACDs. ? Alexander "Sandy" Anderson's role, a new request, is to lead the development of mathematical models in cancer research and integrate these methods into all of the research programs. ? Thomas Brandon continues his role as Staff Investigator leading the tobacco research and intervention group within the Health Outcomes &Behavior Program. He will continue to build collaborative projects with clinical and basic science investigators, such as the Lung Cancer SPORE. ? Srikumar Chellappan's role, a new request, is to integrate Total Cancer Care, mathematics, and imaging resources to develop a translational focused initiative in Tumor Biology. ? B. Lee Green's role, a new request, is to lead the health disparities and diversity efforts at the institution. He will also continue to help build collaborations across programs to address cancer disparities and work closely with the Clinical Trials Office on the difficult task to increase minority accrual in clinical trials and research studies. ? Jeffrey Lancet's role as Clinical Staff Investigator, a new request, is to lead early phase investigator-initiated clinical trials and develop a highly active network of clinical trials using targeted compounds. ? Eduardo Sotomayor's role, a new request, is to integrate and expand laboratory and clinical trial efforts to develop Hematologic Malignancies in the coming years, with joint contributions from Immunology and Experimental Therapeutics. ? Jeffrey Weber's role, a new request, is to integrate and expand laboratory and clinical trial efforts to develop melanoma in the coming years, drawing from multiple programs.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
H. Lee Moffitt Cancer Center & Research Institute
United States
Zip Code
Chung, Brile; Stuge, Tor B; Murad, John P et al. (2014) Antigen-specific inhibition of high-avidity T cell target lysis by low-avidity T cells via trogocytosis. Cell Rep 8:871-82
Charbonneau, Bridget; Block, Matthew S; Bamlet, William R et al. (2014) Risk of ovarian cancer and the NF-*B pathway: genetic association with IL1A and TNFSF10. Cancer Res 74:852-61
Unrod, Marina; Simmons, Vani N; Sutton, Steven K et al. (2014) A randomized clinical trial of self-help intervention for smoking cessation: research design, interventions, and baseline data. Contemp Clin Trials 38:284-90
Osorio, Ana; Milne, Roger L; Kuchenbaecker, Karoline et al. (2014) DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers. PLoS Genet 10:e1004256
Padron, Eric; Yoder, Sean; Kunigal, Sateesh et al. (2014) ETV6 and signaling gene mutations are associated with secondary transformation of myelodysplastic syndromes to chronic myelomonocytic leukemia. Blood 123:3675-7
Hampras, Shalaka S; Viscidi, Raphael P; Helzlsouer, Kathy J et al. (2014) Prospective study of seroreactivity to JC virus T-antigen and risk of colorectal cancers and adenomas. Cancer Epidemiol Biomarkers Prev 23:2591-6
Chen, Ning; Chon, Hye Sook; Xiong, Yin et al. (2014) Human cancer cell line microRNAs associated with in vitro sensitivity to paclitaxel. Oncol Rep 31:376-83
Molife, L Rhoda; Yan, Li; Vitfell-Rasmussen, Joanna et al. (2014) Phase 1 trial of the oral AKT inhibitor MK-2206 plus carboplatin/paclitaxel, docetaxel, or erlotinib in patients with advanced solid tumors. J Hematol Oncol 7:1
Carvalho, Renato S; Fernandes, Vanessa C; Nepomuceno, Thales C et al. (2014) Characterization of LGALS3 (galectin-3) as a player in DNA damage response. Cancer Biol Ther 15:840-50
Rizwani, Wasia; Schaal, Courtney; Kunigal, Sateesh et al. (2014) Mammalian lysine histone demethylase KDM2A regulates E2F1-mediated gene transcription in breast cancer cells. PLoS One 9:e100888

Showing the most recent 10 out of 108 publications