Moffitt proposes 7 staff investigators, each at 10% effort for a total of 8.4 calendar months to serve key leadership roles in the development of focused and translational research, working with the ACD of Translational Research and the other ACDs. ? Alexander "Sandy" Anderson's role, a new request, is to lead the development of mathematical models in cancer research and integrate these methods into all of the research programs. ? Thomas Brandon continues his role as Staff Investigator leading the tobacco research and intervention group within the Health Outcomes &Behavior Program. He will continue to build collaborative projects with clinical and basic science investigators, such as the Lung Cancer SPORE. ? Srikumar Chellappan's role, a new request, is to integrate Total Cancer Care, mathematics, and imaging resources to develop a translational focused initiative in Tumor Biology. ? B. Lee Green's role, a new request, is to lead the health disparities and diversity efforts at the institution. He will also continue to help build collaborations across programs to address cancer disparities and work closely with the Clinical Trials Office on the difficult task to increase minority accrual in clinical trials and research studies. ? Jeffrey Lancet's role as Clinical Staff Investigator, a new request, is to lead early phase investigator-initiated clinical trials and develop a highly active network of clinical trials using targeted compounds. ? Eduardo Sotomayor's role, a new request, is to integrate and expand laboratory and clinical trial efforts to develop Hematologic Malignancies in the coming years, with joint contributions from Immunology and Experimental Therapeutics. ? Jeffrey Weber's role, a new request, is to integrate and expand laboratory and clinical trial efforts to develop melanoma in the coming years, drawing from multiple programs.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
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Subcommittee G - Education (NCI)
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H. Lee Moffitt Cancer Center & Research Institute
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Permuth, Jennifer B; Pirie, Ailith; Ann Chen, Y et al. (2016) Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk. Hum Mol Genet 25:3600-3612
Weber, Jeffrey; Gibney, Geoffrey; Kudchadkar, Ragini et al. (2016) Phase I/II Study of Metastatic Melanoma Patients Treated with Nivolumab Who Had Progressed after Ipilimumab. Cancer Immunol Res 4:345-53
Reed, Damon R; Mascarenhas, Leo; Manning, Kathleen et al. (2016) Pediatric phase I trial of oral sorafenib and topotecan in refractory or recurrent pediatric solid malignancies. Cancer Med 5:294-303
Turner, Joel G; Dawson, Jana L; Grant, Steven et al. (2016) Treatment of acquired drug resistance in multiple myeloma by combination therapy with XPO1 and topoisomerase II inhibitors. J Hematol Oncol 9:73
Haake, Scott M; Li, Jiannong; Bai, Yun et al. (2016) Tyrosine Kinase Signaling in Clear Cell and Papillary Renal Cell Carcinoma Revealed by Mass Spectrometry-Based Phosphotyrosine Proteomics. Clin Cancer Res :
Schabath, Matthew B; Massion, Pierre P; Thompson, Zachary J et al. (2016) Differences in Patient Outcomes of Prevalence, Interval, and Screen-Detected Lung Cancers in the CT Arm of the National Lung Screening Trial. PLoS One 11:e0159880
Kim, Jae-Young; Welsh, Eric A; Fang, Bin et al. (2016) Phosphoproteomics Reveals MAPK Inhibitors Enhance MET- and EGFR-Driven AKT Signaling in KRAS-Mutant Lung Cancer. Mol Cancer Res 14:1019-1029
Extermann, Martine; Leeuwenburgh, Christiaan; Samiian, Laila et al. (2016) Impact of chemotherapy on medium-term physical function and activity of older breast cancer survivors, and associated biomarkers. J Geriatr Oncol :
Jiang, Kun; Neill, Kevin; Cowden, Daniel et al. (2016) Expression of CAS/CSE1L, the Cellular Apoptosis Susceptibility Protein, Correlates With Neoplastic Progression in Barrett's Esophagus. Appl Immunohistochem Mol Morphol :
Sung, Hyeran; Kanchi, Krishna L; Wang, Xue et al. (2016) Inactivation of RASA1 promotes melanoma tumorigenesis via R-Ras activation. Oncotarget 7:23885-96

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