Leadership of the Dan L. Duncan Cancer Center has been fortunate to have an excellent group of internal and external advisors engaged in developing the capabilities of the Center. Based on advice and feedback from the original submission and the advice of our advisors themselves, we have significantly increased the size of our EAB and have brought on individuals who bring a broader range of expertise to provide guidance for the DLDCC. In addition to the EAB, the Center has well developed internal advisory functions including an Executive Committee which reviews and discusses all major decisions and strategic directions and has regular meetings with its Program Leaders and Shared Resource Directors. The Center created a Clinical Research Leadership Committee in 2008 to more effectively ensure that all clinical research conducted within this multi institutional Cancer Center meets the high standards set forth in DLDCC clinical research SOPs and adheres to current federal and state regulations, guidelines, Good Clinical Practices, and BCM Policy. Center and programmatic leadership sponsor retreats, symposium and other activities to effectively plan, communicate and foster scientific interaction. Advice and council, gather from these various groups, as well as intelligence gathered by DLDCC leadership participation in various national and international organizations, is formally reviewed and discussed at annual retreats. This input is then used to inform the development of Strategic Plan that guides decision making and resource allocation on an ongoing basis. Feedback from the formal CCSG review process conducted in 2006 also is incorporated in our plan. The DLDCC Strategic Plan is revised on a regular basis, as goals are completed and new opportunities arise. The Plan was last revised in February 2008, and will be updated as a consequence ofthe CCSG renewal application.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA125123-08
Application #
8690539
Study Section
Subcommittee B - Comprehensiveness (NCI)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
8
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Type
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77030
Bajgain, Pradip; Tawinwung, Supannikar; D'Elia, Lindsey et al. (2018) CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation. J Immunother Cancer 6:34
Badr, Hoda; Herbert, Krista; Bonnen, Mark D et al. (2018) Dyadic Coping in Patients Undergoing Radiotherapy for Head and Neck Cancer and Their Spouses. Front Psychol 9:1780
Morita, Daisuke; Nishio, Nobuhiro; Saito, Shoji et al. (2018) Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells. Mol Ther Methods Clin Dev 8:131-140
Gates, Leah A; Gu, Guowei; Chen, Yue et al. (2018) Proteomic profiling identifies key coactivators utilized by mutant ER? proteins as potential new therapeutic targets. Oncogene 37:4581-4598
Ballester, Leomar Y; Lu, Guangrong; Zorofchian, Soheil et al. (2018) Analysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors. Acta Neuropathol Commun 6:85
Bollard, Catherine M; Tripic, Tamara; Cruz, Conrad Russell et al. (2018) Tumor-Specific T-Cells Engineered to Overcome Tumor Immune Evasion Induce Clinical Responses in Patients With Relapsed Hodgkin Lymphoma. J Clin Oncol 36:1128-1139
Shi, Xiangguo; Kitano, Ayumi; Jiang, Yajian et al. (2018) Clonal expansion and myeloid leukemia progression modeled by multiplex gene editing of murine hematopoietic progenitor cells. Exp Hematol 64:33-44.e5
Dasgupta, Subhamoy; Rajapakshe, Kimal; Zhu, Bokai et al. (2018) Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer. Nature 556:249-254
Qin, Liying; Sankaran, Banumathi; Aminzai, Sahar et al. (2018) Structural basis for selective inhibition of human PKG I? by the balanol-like compound N46. J Biol Chem 293:10985-10992
Chapple, Richard H; Tseng, Yu-Jung; Hu, Tianyuan et al. (2018) Lineage tracing of murine adult hematopoietic stem cells reveals active contribution to steady-state hematopoiesis. Blood Adv 2:1220-1228

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