Leadership of the Dan L. Duncan Cancer Center has been fortunate to have an excellent group of internal and external advisors engaged in developing the capabilities of the Center. Based on advice and feedback from the original submission and the advice of our advisors themselves, we have significantly increased the size of our EAB and have brought on individuals who bring a broader range of expertise to provide guidance for the DLDCC. In addition to the EAB, the Center has well developed internal advisory functions including an Executive Committee which reviews and discusses all major decisions and strategic directions and has regular meetings with its Program Leaders and Shared Resource Directors. The Center created a Clinical Research Leadership Committee in 2008 to more effectively ensure that all clinical research conducted within this multi institutional Cancer Center meets the high standards set forth in DLDCC clinical research SOPs and adheres to current federal and state regulations, guidelines, Good Clinical Practices, and BCM Policy. Center and programmatic leadership sponsor retreats, symposium and other activities to effectively plan, communicate and foster scientific interaction. Advice and council, gather from these various groups, as well as intelligence gathered by DLDCC leadership participation in various national and international organizations, is formally reviewed and discussed at annual retreats. This input is then used to inform the development of Strategic Plan that guides decision making and resource allocation on an ongoing basis. Feedback from the formal CCSG review process conducted in 2006 also is incorporated in our plan. The DLDCC Strategic Plan is revised on a regular basis, as goals are completed and new opportunities arise. The Plan was last revised in February 2008, and will be updated as a consequence ofthe CCSG renewal application.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA125123-08
Application #
8690539
Study Section
Subcommittee B - Comprehensiveness (NCI)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
8
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Type
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77030
Woodard, Lauren E; Cheng, Jizhong; Welch, Richard C et al. (2017) Kidney-specific transposon-mediated gene transfer in vivo. Sci Rep 7:44904
Saxena, Kapil; Simon, Lukas M; Zeng, Xi-Lei et al. (2017) A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection. Proc Natl Acad Sci U S A 114:E570-E579
Heczey, Andras; Louis, Chrystal U; Savoldo, Barbara et al. (2017) CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma. Mol Ther 25:2214-2224
Rohira, Aarti D; Yan, Fei; Wang, Lei et al. (2017) Targeting SRC Coactivators Blocks the Tumor-Initiating Capacity of Cancer Stem-like Cells. Cancer Res 77:4293-4304
Ware, Matthew J; Nguyen, Lam P; Law, Justin J et al. (2017) A new mild hyperthermia device to treat vascular involvement in cancer surgery. Sci Rep 7:11299
Gibbons, Don L; Creighton, Chad J (2017) Pan-cancer survey of epithelial-mesenchymal transition markers across the Cancer Genome Atlas. Dev Dyn :
Ha, Kyungsoo; Ma, Chengxian; Lin, Han et al. (2017) The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites. Nat Commun 8:15751
Schmueck-Henneresse, Michael; Omer, Bilal; Shum, Thomas et al. (2017) Comprehensive Approach for Identifying the T Cell Subset Origin of CD3 and CD28 Antibody-Activated Chimeric Antigen Receptor-Modified T Cells. J Immunol 199:348-362
Wang, Yongquan; Wang, Jianghua; Zhang, Li et al. (2017) RGS12 Is a Novel Tumor-Suppressor Gene in African American Prostate Cancer That Represses AKT and MNX1 Expression. Cancer Res 77:4247-4257
Sreekumar, Amulya; Toneff, Michael J; Toh, Eajer et al. (2017) WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis. Dev Cell 43:436-448.e6

Showing the most recent 10 out of 842 publications