Strong planning and evaluation has been critical for the development of the research infrastructure at the Hollings Cancer Center (HCC) and is carried out through multiple feed back mechanisms, both external and internal. The HCC External Scientific Advisory Board is the primary external mechanism for review and advice on the HCC's progress in research. Internal mechanisms include the advice and counsel of HCC's Senior Leaders who formally comprise the HCC Executive Council;the HCC Research Committee;an Internal Scientific Advisory Board that meets annually and is comprised of MUSC institutional leaders and officials;and a Clinical Research Oversight Committee. Other planning and evaluation efforts occur at the program and shared resource levels. In 2005, Dr. Kraft and the Senior Leadership developed a strategic road map to guide the HCC development over a five year period. This road map outlines nine strategic directions for research to be developed, the need for expanded services within existing shared research resources as well as new shared research resources, and organizational strategies to improve collaboration and interdisciplinary interactions. This road map is regularly re-visited, reviewed for progress and updated specifically with the input of new members of the Senior Leadership team as they have come on board.
The ongoing and clearly defined formative and summative evaluation and planning processes of the Hollings Cancer Center has been key to its growth in research in terms of extramural funding, enrollment onto clinical trials and dissemination of research results in the medical literature.
|Song, J H; An, N; Chatterjee, S et al. (2015) Deletion of Pim kinases elevates the cellular levels of reactive oxygen species and sensitizes to K-Ras-induced cell killing. Oncogene 34:3728-36|
|Zemskova, Marina Y; Song, Jin H; Cen, Bo et al. (2015) Regulation of prostate stromal fibroblasts by the PIM1 protein kinase. Cell Signal 27:135-46|
|Boppana, Nithin B; Kodiha, Mohamed; Stochaj, Ursula et al. (2014) Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization. Photochem Photobiol Sci 13:1621-7|
|God, Jason M; Zhao, Dan; Cameron, Christine A et al. (2014) Disruption of HLA class II antigen presentation in Burkitt lymphoma: implication of a 47,000 MW acid labile protein in CD4+ T-cell recognition. Immunology 142:492-505|
|Esnaola, Nestor F; Chaudhary, Uzair B; O'Brien, Paul et al. (2014) Phase 2 trial of induction gemcitabine, oxaliplatin, and cetuximab followed by selective capecitabine-based chemoradiation in patients with borderline resectable or unresectable locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys 88:837-44|
|Fuseler, John W; Robichaux, Jacqulyne P; Atiyah, Huda I et al. (2014) Morphometric and fractal dimension analysis identifies early neoplastic changes in mammary epithelium of MMTV-cNeu mice. Anticancer Res 34:1171-7|
|Hussey, Sophie E; Lum, Helen; Alvarez, Andrea et al. (2014) A sustained increase in plasma NEFA upregulates the Toll-like receptor network in human muscle. Diabetologia 57:582-91|
|Chen, Weiqin; Zhou, Hongyi; Saha, Pradip et al. (2014) Molecular mechanisms underlying fasting modulated liver insulin sensitivity and metabolism in male lipodystrophic Bscl2/Seipin-deficient mice. Endocrinology 155:4215-25|
|Kesarwani, Pravin; Al-Khami, Amir A; Scurti, Gina et al. (2014) Promoting thiol expression increases the durability of antitumor T-cell functions. Cancer Res 74:6036-47|
|He, Huacheng; Cattran, Alexander W; Nguyen, Tu et al. (2014) Triple-responsive expansile nanogel for tumor and mitochondria targeted photosensitizer delivery. Biomaterials 35:9546-53|
Showing the most recent 10 out of 162 publications