Developmental Funds have been essential for catalyzing growth and developing scientific depth for the Simmons Cancer Center's scientific programs. A planning and evaluafion process sets strategic and programmatic priorifies with input from program leaders and oversight by senior leadership and external advisors. The Simmons Cancer Center has grown rapidly over the past 4 years with strong philanthropic and institufional support for recruitment of new scienfists and clinical invesfigators from outside the institution. Insfitutional resources have been committed for the continued expansion of the Cancer Center with plans for recruitment of 15 new faculty to address areas of strategic need within the Center. Particular emphasis will be on the development of a program of excellence in breast cancer, an early phase clinical trials inifiafive with particular focus in phase I trials, and a cancer control and population science program that focuses on behavioral and health communicafion research. Developmental Funds from the Cancer Center Support Grant will be used to support (1) new investigator projects;and (2) pilot projects that will encourage new areas of cancer research. The CCSG funds will be supplemented with insfitutional resources to provide funding for 8 new invesfigator awards at $40,000 each and to provide $200,000 for pilot projects. A new invesfigator project oversight committee will evaluate and rank pilot projects for funding. Advocacy for novel innovafive and high risk pilot projects will come from program leadership and be evaluated for support by the Senior Leadership Council.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA142543-05
Application #
8711029
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
5
Fiscal Year
2014
Total Cost
$94,401
Indirect Cost
$1,856
Name
University of Texas Sw Medical Center Dallas
Department
Type
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Wong, Mandy S; Wright, Woodring E; Shay, Jerry W (2014) Alternative splicing regulation of telomerase: a new paradigm? Trends Genet 30:430-8
Chau, Vincent; Lim, S Kyun; Mo, Wei et al. (2014) Preclinical therapeutic efficacy of a novel pharmacologic inducer of apoptosis in malignant peripheral nerve sheath tumors. Cancer Res 74:586-97
Iscla, Irene; Wray, Robin; Wei, Shuguang et al. (2014) Streptomycin potency is dependent on MscL channel expression. Nat Commun 5:4891
Fu, Peng; Johnson, Melissa; Chen, Hong et al. (2014) Carpatamides A-C, cytotoxic arylamine derivatives from a marine-derived Streptomyces sp. J Nat Prod 77:1245-8
Park, Jason Y; Gunpat, Joshua; Liu, Li et al. (2014) Red-shifted emission from 1,2-dioxetane-based chemiluminescent reactions. Luminescence 29:553-8
Gerber, David E; Laccetti, Andrew L; Xuan, Lei et al. (2014) Impact of prior cancer on eligibility for lung cancer clinical trials. J Natl Cancer Inst 106:
Yang, Liu; Kwon, Junghee; Popov, Yury et al. (2014) Vascular endothelial growth factor promotes fibrosis resolution and repair in mice. Gastroenterology 146:1339-50.e1
Li, Biaoru; Ding, Lianghao; Yang, Chinrang et al. (2014) Characterization of transcription factor networks involved in umbilical cord blood CD34+ stem cells-derived erythropoiesis. PLoS One 9:e107133
Ludlow, Andrew T; Robin, Jerome D; Sayed, Mohammed et al. (2014) Quantitative telomerase enzyme activity determination using droplet digital PCR with single cell resolution. Nucleic Acids Res 42:e104
King, Kelly A; Gordon-Salant, Sandra; Pawlowski, Karen S et al. (2014) Hearing loss is an early consequence of Npc1 gene deletion in the mouse model of Niemann-Pick disease, type C. J Assoc Res Otolaryngol 15:529-41

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