Five years ago, the Tufts Nutrition Collaborative - Center for Drug Abuse and AIDS Research (TNC-CDAAR) was funded by NIDA as just one of two CDAAR's in the nation. The CDAARs were charged with the following mission: to foster a collaborative approach to drug abuse and addiction research;to enable studies that would not occur without the climate, facilities, and resources that a research center can uniquely provide;to serve as a resource to attract established and promising investigators into drug abuse research;and to provide opportunities for research training, career development, and mentoring. The TNC-CDAAR was formed as a partnership between three East Coast Institutions (Tufts, Brown and Johns Hopkins) with a specific focus on studying nutritional and .metabolic disorders among HIV-positive and HIV-negative drug users. Over the past five years, we have expanded the TNC-CDAAR to include collaborators from 3 international sites: Argentina, India, and Vietnam. Our major accomplishments, thus far, have been to 1) design and implement several new studies to assess and compare the prevalence and incidence of specific nutritional and metabolic disorders in drug users of different ethnicities, both in the U.S. and abroad;2) develop training materials, protocols, and manuals for investigators who want to undertake similar studies in their localities;3) help in the development of new grant proposals in Center-related areas of research;and 4) become a resource center on nutrition and metabolic disorders in drug users. The TNC-CDAAR will continue to operate five of its original six cores: Administrative (Core A), Developmental (Core B);Drug User Resources (Core C);Nutrition and Metabolism (Core D);and Epidemiology and Biostatistics (Core F). Core E (Endocrine) will be merged with Core D and a new Core on Hepatitis and Liver Function (Core G) will be added. This new Core was developed in response to the needs of TNC-CDAAR Investigators and Members who have found that nutritional and metabolic abnormalities are likely linked not only to HIV, but also to chronic liver disease among persons who use drugs. The Center will continue to work to raise awareness of the importance of nutritional and metabolic disorders on outcomes in the drug using population and to encourage investigators to include studies of nutritional and metabolic status in their research in drug using populations. The five Center Cores will continue to work synergistically to provide a multitude of services for Center Members.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Center Core Grants (P30)
Project #
5P30DA013868-10
Application #
8306308
Study Section
Special Emphasis Panel (ZDA1-RXL-E (02))
Program Officer
Khalsa, Jagjitsingh H
Project Start
2000-09-01
Project End
2014-07-31
Budget Start
2012-08-01
Budget End
2014-07-31
Support Year
10
Fiscal Year
2012
Total Cost
$806,067
Indirect Cost
$368,049
Name
Tufts University
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
039318308
City
Boston
State
MA
Country
United States
Zip Code
02111
Lambert, Allison A; Kirk, Gregory D; Astemborski, Jacquie et al. (2014) A cross sectional analysis of the role of the antimicrobial peptide cathelicidin in lung function impairment within the ALIVE cohort. PLoS One 9:e95099
Dugdale, Caitlin; Zaller, Nickolas; Bratberg, Jeffrey et al. (2014) Missed opportunities for HIV screening in pharmacies and retail clinics. J Manag Care Spec Pharm 20:339-45
Lambert, Allison A; Drummond, M Bradley; Mehta, Shruti H et al. (2014) Risk factors for vitamin D deficiency among HIV-infected and uninfected injection drug users. PLoS One 9:e95802
Hong, Steven Y; Fanelli, Theresa J; Jonas, Anna et al. (2014) Household food insecurity associated with antiretroviral therapy adherence among HIV-infected patients in Windhoek, Namibia. J Acquir Immune Defic Syndr 67:e115-22
Volpe, Gretchen E; Ward, Honorine; Mwamburi, Mkaya et al. (2014) Associations of cocaine use and HIV infection with the intestinal microbiota, microbial translocation, and inflammation. J Stud Alcohol Drugs 75:347-57
Jarrett, Olamide D; Wanke, Christine A; Ruthazer, Robin et al. (2013) Metabolic syndrome predicts all-cause mortality in persons with human immunodeficiency virus. AIDS Patient Care STDS 27:266-71
Westergaard, Ryan P; Spaulding, Anne C; Flanigan, Timothy P (2013) HIV among persons incarcerated in the USA: a review of evolving concepts in testing, treatment, and linkage to community care. Curr Opin Infect Dis 26:10-6
Flanigan, Timothy P (2013) Jails: the new frontier. HIV testing, treatment, and linkage to care after release. AIDS Behav 17 Suppl 2:S83-5
Sheehan, Heidi B; Benetucci, Jorge; Muzzio, Estela et al. (2012) High rates of serum selenium deficiency among HIV- and HCV-infected and uninfected drug users in Buenos Aires, Argentina. Public Health Nutr 15:538-45
Dumont, Dora M; Brockmann, Brad; Dickman, Samuel et al. (2012) Public health and the epidemic of incarceration. Annu Rev Public Health 33:325-39

Showing the most recent 10 out of 68 publications