The Center for Translational and Prevention Science (CTAPS) was funded in 2009 to inform the development of prevention programs for rural African American youth through investigations of gene environment (G-E) interplay on drug use and HIV-related behavior. The proposed continuation augments CTAPS'scientific agenda to better address racial disparities in drug use and HIV-related behavior that affect rural African Americans. Emerging research suggests that exposure to chronic stress affects the functioning of inflammatory, neuroendocrine, and neurocognitive systems beginning in childhood and adolescence. The negative consequences of chronic stress affect health-related behaviors and forecast chronic diseases of aging. Emerging evidence suggests that these processes also may affect youth and young adults'development of drug misuse and HIV related behavior. The Center will sponsor a new generation of research on (a) the neuroendocrine, inflammatory, and neurocognitive pathways through which exposure to stress among rural African American youth and young adults creates vulnerabilities to drug use and HIV related behavior, (b), the malleable risk and protective processes that affect underlying vulnerability mechanisms , and (c) the translation of findings into new and refined preventive interventions for youth in general and rural African American youth in particular. The CTAPS will pursue these scientific goals via providing infrastructure for three support cores (Inflammation/Neuroendocrine, Neurocognitive, Biostatistics) that will enrich data from data from Core projects and pilot projects and a Pilot Core. CTAPS will facilitate communication among Center-affiliated investigators, support core directors, and core project PIs;oversee administration of Center-wide budgets and operations;provide infrastructure and administrative support for three support cores and a Pilot Core. CTAPS will spur progress via a transdisciplinary work group system designed to facilitate transdisciplinary collaboration and to organize the allocation of Center resources and disseminate research findings to multiple stakeholders including researchers, policy makers, educational organizations, and the public.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Center Core Grants (P30)
Project #
2P30DA027827-06
Application #
8785785
Study Section
Special Emphasis Panel (ZDA1)
Program Officer
Crump, Aria
Project Start
2009-12-01
Project End
2019-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
6
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Georgia
Department
Psychology
Type
Organized Research Units
DUNS #
City
Athens
State
GA
Country
United States
Zip Code
30602
Levine, Cynthia S; Basu, Devika; Chen, Edith (2017) Just World Beliefs Are Associated With Lower Levels of Metabolic Risk and Inflammation and Better Sleep After an Unfair Event. J Pers 85:232-243
Zapolski, Tamika C B; Banks, Devin E; Lau, Katherine S L et al. (2017) Perceived Police Injustice, Moral Disengagement, and Aggression Among Juvenile Offenders: Utilizing the General Strain Theory Model. Child Psychiatry Hum Dev :
Kogan, Steven M; Cho, Junhan; Brody, Gene H et al. (2017) Pathways linking marijuana use to substance use problems among emerging adults: A prospective analysis of young Black men. Addict Behav 72:86-92
Brody, Gene H; Yu, Tianyi; Chen, Edith et al. (2017) Family-centered prevention ameliorates the association between adverse childhood experiences and prediabetes status in young black adults. Prev Med 100:117-122
Windle, Michael; Windle, Rebecca C (2017) The Measurement of Adolescent Alcohol Problems via Item Response Theory and Their 15-Year Prospective Associations with Alcohol and Other Psychiatric Disorders. Alcohol Clin Exp Res 41:399-406
Amlung, Michael; Vedelago, Lana; Acker, John et al. (2017) Steep delay discounting and addictive behavior: a meta-analysis of continuous associations. Addiction 112:51-62
Hostinar, Camelia E; Davidson, Richard J; Graham, Eileen K et al. (2017) Frontal brain asymmetry, childhood maltreatment, and low-grade inflammation at midlife. Psychoneuroendocrinology 75:152-163
Kogan, Steven M; Cho, Junhan; Oshri, Assaf et al. (2017) The influence of substance use on depressive symptoms among young adult black men: The sensitizing effect of early adversity. Am J Addict 26:400-406
Davis, Molly; Thomassin, Kristel; Bilms, Joanie et al. (2017) Preschoolers' genetic, physiological, and behavioral sensitivity factors moderate links between parenting stress and child internalizing, externalizing, and sleep problems. Dev Psychobiol 59:473-485
Barton, Allen W; Beach, Steven R H; Lavner, Justin A et al. (2017) Is Communication a Mechanism of Relationship Education Effects among Rural African Americans? J Marriage Fam 79:1450-1461

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