The Computer Resources Core (Core B) provides a spectrum of services to support and enhance the research endeavors of a core group of scientists investigating questions related to hearing, communication and balance at the University of Washington. The overall goal is to increase the productivity of our research through better use of computers. Specifically, we aim to: enable completely new types of research;accelerate development and spread of technologies new to the University of Washington;facilitate collaboration or interaction among users of the Core;help reduce redundant work by providing consolidated computer expertise accessible by all users of the core;maintain a high level of basic computer support for all supported research groups. We endeavor to provide computer expertise within a broad enough scientific context that any one solution would have potential for more than one application. In consultation with the members of the Core, the Computer Specialists supported by the Core will select a software package or develop custom software to fit the goals of the experiment or analysis desired. The Computer Specialists are responsible for testing and debugging software applications and training and assisting core users to apply the software in their research. Likewise, hardware solutions will be implemented in a similar manner. The Computer Specialists will also help to disseminate information about solutions to particular problems to other Core investigators who might be able to incorporate such solutions into their.own research.
Increasing the efficiency and efficacy of research on hearing, communication and balance will help, in the short term, bring new therapies to the bedside. In the long term, better understanding of the basic normal operation of the organs and systems underiying these functions, as well as the processes leading to disorders, is likely to lead to better prevention and treatment of such disorders and to improved human health.
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|Minich, Rebecca R; Li, Jin; Tempel, Bruce L (2017) Early growth response protein 1 regulates promoter activity of ?-plasma membrane calcium ATPase 2, a major calcium pump in the brain and auditory system. BMC Mol Biol 18:14|
|Cabrera, Laurianne; Werner, Lynne (2017) Infants' and Adults' Use of Temporal Cues in Consonant Discrimination. Ear Hear 38:497-506|
|Bucks, Stephanie A; Cox, Brandon C; Vlosich, Brittany A et al. (2017) Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice. Elife 6:|
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|DeVries, Lindsay; Scheperle, Rachel; Bierer, Julie Arenberg (2016) Assessing the Electrode-Neuron Interface with the Electrically Evoked Compound Action Potential, Electrode Position, and Behavioral Thresholds. J Assoc Res Otolaryngol 17:237-52|
|Miller, Christi W; Bates, Emily; Brennan, Marc (2016) The effects of frequency lowering on speech perception in noise with adult hearing-aid users. Int J Audiol 55:305-12|
|Esterberg, Robert; Linbo, Tor; Pickett, Sarah B et al. (2016) Mitochondrial calcium uptake underlies ROS generation during aminoglycoside-induced hair cell death. J Clin Invest 126:3556-66|
|Slowik, Amber D; Bermingham-McDonogh, Olivia (2016) A central to peripheral progression of cell cycle exit and hair cell differentiation in the developing mouse cristae. Dev Biol 411:1-14|
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