CORE A: LABORATORY COMPUTING &BIOSTATISTICS CORE The purpose of this core is to increase the productivity of ongoing research at BTNRH by providing easier access to professionals with expertise related to laboratory computing and biostatistics. Most of the research projects that constitute the research base for this core require the presentation and/or acquisition of digitized waveforms. Some of these research projects elicit behavioral, acoustical, and electrophysiological responses for the same auditory stimuli. In many instances, similar hypotheses are being evaluated using different approaches. The parallel nature of these research efforts produces considerable overlap in hardware and software needs. Our existing Laboratory Computing Facility is staffed by full-time technicians who split their effort between this Core and individual ROIs. These technicians provide many of the hardware and software needs of the research base, thereby enhancing productivity in these research projects. By maintaining familiarity with ongoing data acquisition efforts of the research base, Core technicians are in an ideal position to identify common needs and promote a cooperative interaction among investigators. Software developed by Core technicians is made available to researchers at other institutions at no cost. Our proposed Biostatistics Resource will provide onsite access a to a PhD statistician who will provide advice on the implementation of modern statistical methods. The Laboratory Computing &Biostatistics Core allows BTNRH to maintain a higher level of computing-related and statistical expertise than would otherwise be possible through the independent efforts of individual laboratories. The immediate accessibility of this expertise allows our investigators to have greater focus on scientific issues and pursue their research projects more efficiently. As part of the expanded Core Center for Communication Disorders, services will be provided to members of the research base at neighboring institutions.

Public Health Relevance

This Core makes health-related research studies more productive by providing computer support and statistical consultation specific to the conduct of research. Because these support services can be provided more efficiently by a centralized Core, the Core accelerates progress in the research programs that it supports.

National Institute of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
Center Core Grants (P30)
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Special Emphasis Panel (ZDC1-SRB-Q (67))
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Father Flanagan's Boys' Home
Boys Town
United States
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Hughes, Michelle L; Laurello, Sarah A (2017) Effect of stimulus level on the temporal response properties of the auditory nerve in cochlear implants. Hear Res 351:116-129
Nishi, Kanae; Trevino, Andrea C; Rosado Rogers, Lydia et al. (2017) Effects of Simulated Hearing Loss on Bilingual Children's Consonant Recognition in Noise. Ear Hear 38:e292-e304
Hughes, Michelle L; Goehring, Jenny L; Baudhuin, Jacquelyn L (2017) Effects of Stimulus Polarity and Artifact Reduction Method on the Electrically Evoked Compound Action Potential. Ear Hear 38:332-343
Goehring, Jenny L; Hughes, Michelle L (2017) Measuring Sound-Processor Threshold Levels for Pediatric Cochlear Implant Recipients Using Conditioned Play Audiometry via Telepractice. J Speech Lang Hear Res 60:732-740
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Lewis, Dawna; Kopun, Judy; McCreery, Ryan et al. (2017) Effect of Context and Hearing Loss on Time-Gated Word Recognition in Children. Ear Hear 38:e180-e192
Keefe, Douglas H; Feeney, M Patrick; Hunter, Lisa L et al. (2017) Aural Acoustic Stapedius-Muscle Reflex Threshold Procedures to Test Human Infants and Adults. J Assoc Res Otolaryngol 18:65-88
Brennan, Marc A; Lewis, Dawna; McCreery, Ryan et al. (2017) Listening Effort and Speech Recognition with Frequency Compression Amplification for Children and Adults with Hearing Loss. J Am Acad Audiol 28:823-837
Putterman, Daniel B; Keefe, Douglas H; Hunter, Lisa L et al. (2017) Assessing Sensorineural Hearing Loss Using Various Transient-Evoked Otoacoustic Emission Stimulus Conditions. Ear Hear 38:507-520
Lewis, Dawna E; Smith, Nicholas A; Spalding, Jody L et al. (2017) Looking Behavior and Audiovisual Speech Understanding in Children With Normal Hearing and Children With Mild Bilateral or Unilateral Hearing Loss. Ear Hear :

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