Public Health Relevance

The gene revolution has led to the creation of a vast number of transgenic and gene knockout rodent models. These represent a virtual goldmine for new insights into sensory function and dysfunction, but that potential can only be realized if new models are comprehensively examined both anatomically and functionally. The Functional Testing Core promotes thorough and rigorous functional analysis of inner ear and visual function so that the value for public health of new animal models can be fully realized.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Center Core Grants (P30)
Project #
2P30DC004665-11
Application #
8125645
Study Section
Special Emphasis Panel (ZDC1-SRB-Q (64))
Project Start
Project End
Budget Start
2011-09-01
Budget End
2012-08-31
Support Year
11
Fiscal Year
2011
Total Cost
$200,631
Indirect Cost
Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Ohlemiller, Kevin K; Kaur, Tejbeer; Warchol, Mark E et al. (2018) The endocochlear potential as an indicator of reticular lamina integrity after noise exposure in mice. Hear Res 361:138-151
Kaur, Tejbeer; Ohlemiller, Kevin K; Warchol, Mark E (2018) Genetic disruption of fractalkine signaling leads to enhanced loss of cochlear afferents following ototoxic or acoustic injury. J Comp Neurol 526:824-835
Teisher, J K; McKain, M R; Schaal, B A et al. (2017) Polyphyly of Arundinoideae (Poaceae) and evolution of the twisted geniculate lemma awn. Ann Bot 120:725-738
Warchol, Mark E; Stone, Jennifer; Barton, Matthew et al. (2017) ADAM10 and ?-secretase regulate sensory regeneration in the avian vestibular organs. Dev Biol 428:39-51
Morley, Barbara J; Dolan, David F; Ohlemiller, Kevin K et al. (2017) Generation and Characterization of ?9 and ?10 Nicotinic Acetylcholine Receptor Subunit Knockout Mice on a C57BL/6J Background. Front Neurosci 11:516
Graboyes, Evan M; Kallogjeri, Dorina; Saeed, Mohammed J et al. (2017) Postoperative care fragmentation and thirty-day unplanned readmissions after head and neck cancer surgery. Laryngoscope 127:868-874
Graboyes, Evan M; Kallogjeri, Dorina; Saeed, Mohammed J et al. (2017) 30-day hospital readmission following otolaryngology surgery: Analysis of a state inpatient database. Laryngoscope 127:337-345
Kim, Alfred Hj; Chung, Jun-Jae; Akilesh, Shreeram et al. (2017) B cell-derived IL-4 acts on podocytes to induce proteinuria and foot process effacement. JCI Insight 2:
Kao, W Katherine; Gagnon, Patricia M; Vogel, Joseph P et al. (2017) Surface charge modification decreases Pseudomonas aeruginosa adherence in vitro and bacterial persistence in an in vivo implant model. Laryngoscope 127:1655-1661
Kao, Wee Tin K; Parnes, Lorne S; Chole, Richard A (2017) Otoconia and otolithic membrane fragments within the posterior semicircular canal in benign paroxysmal positional vertigo. Laryngoscope 127:709-714

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