The Research Center for Auditory and Vestibular Studies (RCAVS), housed in the Department of Otolaryngology at Washington University School of Medicine, is a full service centralized facility that was developed to support the scientific progress of funded research in mission areas of the NIDCD. The Core Center is composed of four individual Research Cores and an Administrative Shell which interact to fulfill the aims of the Center. The areas in which services are offered include: Functional Testing, Histology, Microscopy &Digital Imaging and Clinical &Translational Research. Although core services are primarily designed to assist member projects that constitute the Qualifying Research Base, services are also offered, as available, to non-qualifying projects in NIDCD mission areas as well as outside projects. The Adminstrative Shell is coordinated through the Center Executive Committee, composed of the Center Director and individual Research Core Directors. Ancillary personnel include a Research Administrator and Newsletter/Website Manager. The Administrative Shell provides oversight of individual Research Core activities, facilitates interactions between cores, coordinates Center-wide activities such as the bimonthly Research Seminar and journal clubs, provides budgetary guidance for the purchase of supplies and equipment, prepares re-charge requests for core services provided to non-members, produces the Center newsletter and manages the Center website. The Administrative Shell also guides development of the Specific Aims of the RCAVS which include the following: 1) To provide centralized equipment and services for investigators whose research overlaps mission areas of the NIDCD;2) to encourage collaborative efforts, support the development of new research questions by core members and attract new researchers to mission areas of the NIDCD;and 3) to promote translational research via mechanisms designed to enhance scientific interactions and collaborations between basic and clinical scientists. The ultimate impact of this application is to facilitate progress in the development of treatments for human disorders of hearing, balance and speech and to serve as a model for a successful translational research program.

Public Health Relevance

The P30 Research Core Center creates centralized resources to facilitate the scientific progress of investigators conducting research in mission areas of the NIDCD. It provides technical assistance, training, and equipment at a level that is not feasible for individual investigators and is designed to promote scientific interaction, collaboration and translational research. Highlighted areas of support include Functional Testing, Histology, Microscopy &Digital Imaging, and Clinical &Translational Research.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Center Core Grants (P30)
Project #
5P30DC004665-13
Application #
8529206
Study Section
Special Emphasis Panel (ZDC1-SRB-Q)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
13
Fiscal Year
2013
Total Cost
$12,768
Indirect Cost
$4,368
Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Ohlemiller, Kevin K; Kaur, Tejbeer; Warchol, Mark E et al. (2018) The endocochlear potential as an indicator of reticular lamina integrity after noise exposure in mice. Hear Res 361:138-151
Kaur, Tejbeer; Ohlemiller, Kevin K; Warchol, Mark E (2018) Genetic disruption of fractalkine signaling leads to enhanced loss of cochlear afferents following ototoxic or acoustic injury. J Comp Neurol 526:824-835
Teisher, J K; McKain, M R; Schaal, B A et al. (2017) Polyphyly of Arundinoideae (Poaceae) and evolution of the twisted geniculate lemma awn. Ann Bot 120:725-738
Warchol, Mark E; Stone, Jennifer; Barton, Matthew et al. (2017) ADAM10 and ?-secretase regulate sensory regeneration in the avian vestibular organs. Dev Biol 428:39-51
Morley, Barbara J; Dolan, David F; Ohlemiller, Kevin K et al. (2017) Generation and Characterization of ?9 and ?10 Nicotinic Acetylcholine Receptor Subunit Knockout Mice on a C57BL/6J Background. Front Neurosci 11:516
Graboyes, Evan M; Kallogjeri, Dorina; Saeed, Mohammed J et al. (2017) Postoperative care fragmentation and thirty-day unplanned readmissions after head and neck cancer surgery. Laryngoscope 127:868-874
Graboyes, Evan M; Kallogjeri, Dorina; Saeed, Mohammed J et al. (2017) 30-day hospital readmission following otolaryngology surgery: Analysis of a state inpatient database. Laryngoscope 127:337-345
Kim, Alfred Hj; Chung, Jun-Jae; Akilesh, Shreeram et al. (2017) B cell-derived IL-4 acts on podocytes to induce proteinuria and foot process effacement. JCI Insight 2:
Kao, W Katherine; Gagnon, Patricia M; Vogel, Joseph P et al. (2017) Surface charge modification decreases Pseudomonas aeruginosa adherence in vitro and bacterial persistence in an in vivo implant model. Laryngoscope 127:1655-1661
Kao, Wee Tin K; Parnes, Lorne S; Chole, Richard A (2017) Otoconia and otolithic membrane fragments within the posterior semicircular canal in benign paroxysmal positional vertigo. Laryngoscope 127:709-714

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