The administrative shell has an organizational rather than a scientific focus. While the goals of the individual Cores are to serve the user base, the goal of the administrative shell is to serve the individual cores, overarching needs and the overall Research Core Center mission. The charge to the administrative shell is therefore to:
Specific Aim 1 : Integrate and supervise the Research Core Center activities Specific Aim 2: Facilitate the operation of the individual cores by resolving issues of space and facilities Specific Aim 3: Assume administrative tasks for all cores such as personnel management and financial operations Specific Aim 4: Carry out or facilitate contacts with University of Michigan administration and granting agencies Specific Aim 5: Coordinate and facilitate the submission of progress reports and renewal grant applications Specific Aim 6: Track user group research and publications associated with their use of the Core Specific Aim 7: Coordinate training across Core components Specific Aim 8: Coordinate and maintain the Research Core Center web site

Public Health Relevance

The purpose of this grant is to enhance and extend the research of multiple investigators towards increasing the understanding of disorders of hearing, balance, taste and smell and developing the ability to prevent and treat these disorders. It will also provide mechanisms to encourage and increase collaborations among its research base, bring new researchers into the field as well as educate the user base on new methods and approaches.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Center Core Grants (P30)
Project #
5P30DC005188-12
Application #
8501413
Study Section
Special Emphasis Panel (ZDC1-SRB-L)
Project Start
Project End
Budget Start
2013-07-31
Budget End
2014-07-30
Support Year
12
Fiscal Year
2013
Total Cost
$208,914
Indirect Cost
$74,564
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Pfingst, Bryan E; Zhou, Ning; Colesa, Deborah J et al. (2015) Importance of cochlear health for implant function. Hear Res 322:77-88
Owen, John H; Hauff, Samantha J; Tang, Alice L et al. (2014) UM-SCC-103: a unique tongue cancer cell line that recapitulates the tumorigenic stem cell population of the primary tumor. Ann Otol Rhinol Laryngol 123:662-72
Takada, Yohei; Beyer, Lisa A; Swiderski, Donald L et al. (2014) Connexin 26 null mice exhibit spiral ganglion degeneration that can be blocked by BDNF gene therapy. Hear Res 309:124-35
Park, Yong-Ho; Wilson, Kevin F; Ueda, Yoshihisa et al. (2014) Conditioning the cochlea to facilitate survival and integration of exogenous cells into the auditory epithelium. Mol Ther 22:873-80
Le Prell, Colleen G; Dolan, David F; Hughes, Larry F et al. (2014) Disruption of lateral olivocochlear neurons with a dopaminergic neurotoxin depresses spontaneous auditory nerve activity. Neurosci Lett 582:54-8
Imtiaz, Ayesha; Kohrman, David C; Naz, Sadaf (2014) A frameshift mutation in GRXCR2 causes recessively inherited hearing loss. Hum Mutat 35:618-24
Micucci, Joseph A; Layman, Wanda S; Hurd, Elizabeth A et al. (2014) CHD7 and retinoic acid signaling cooperate to regulate neural stem cell and inner ear development in mouse models of CHARGE syndrome. Hum Mol Genet 23:434-48
Rudnicki, Anya; Shivatzki, Shaked; Beyer, Lisa A et al. (2014) microRNA-224 regulates Pentraxin 3, a component of the humoral arm of innate immunity, in inner ear inflammation. Hum Mol Genet 23:3138-46
Zhou, Ning; Pfingst, Bryan E (2014) Effects of site-specific level adjustments on speech recognition with cochlear implants. Ear Hear 35:30-40
Zhou, Ning; Pfingst, Bryan E (2014) Relationship between multipulse integration and speech recognition with cochlear implants. J Acoust Soc Am 136:1257

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