The Instrument Design and Technical Services Core comprises facilities and personnel for three units: Electronic Engineering, Mechanical Engineering, and Information Technology. These units assure the efficient operation of all scientific programs, facilitate innovative technical solutions, and foster new research initiatives through assistance with design, troubleshooting, maintenance, and product procurements. Dr. Keith Duncan will serve as the Core Director. He will facilitate dialog between Technical Core personnel, other components of the Core Center, and the user base, in order to maximize user satisfaction, assist with prioritization when necessary, and ensure that the resources are available to maintain core efficacy. The Electronic and Mechanical Engineering units will provide innovative design, fabrication, maintenance, and calibration of custom instruments. Personnel are experienced in each stage of project development from conceptualization to design, fabrication, installation, and calibration. Electronic Engineering is capable of analog and digital instrument design within the rather unique context of auditory and vestibular research. Mechanical Engineering is capable of the design, fabrication, maintenance, and repair of micro- and large-scale devices constructed with a large range of materials. Information Technology supports the network infrastructure of the Core Center and user base laboratories, provides data management tools, oversees hardware/software issues particularly as they are applied to custom interfaces and instrumentation, and is responsible for web-based interfaces. The Information Technology unit will inform faculty of new developments in computer and software resources, provide acquisition advice, and facilitate database management of Core Center activities. The Technical Core will enhance research programs by providing innovative technical solutions (Specific Aim 1), improve efficiency by providing on-site maintenance, repair, calibration, and customization (Specific Aim 2), meet current and future user needs by maintaining a familiarity with the science they server (Specific Aim 3), and build bridges among the user base and broader research community to foster technical collaboration (Specific Aim 4).

Public Health Relevance

The purpose of this grant is to enhance and extend the research of multiple investigators towards increasing the understanding of disorders of hearing, balance, taste and smell and developing the ability to prevent and treat these disorders. It will also provide mechanisms to encourage and increase collaborations among its research base, bring new researchers into the field as well as educate the user base on new methods and approaches.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Center Core Grants (P30)
Project #
5P30DC005188-13
Application #
8696845
Study Section
Special Emphasis Panel (ZDC1)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
13
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Carlson, Krystin; Schacht, Jochen; Neitzel, Richard L (2018) Assessing ototoxicity due to chronic lead and cadmium intake with and without noise exposure in the mature mouse. J Toxicol Environ Health A 81:1041-1057
Schaefer, Stacy A; Higashi, Atsuko Y; Loomis, Benjamin et al. (2018) From Otic Induction to Hair Cell Production: Pax2EGFP Cell Line Illuminates Key Stages of Development in Mouse Inner Ear Organoid Model. Stem Cells Dev 27:237-251
Heeringa, Amarins N; Wu, Calvin; Chung, Christopher et al. (2018) Glutamatergic Projections to the Cochlear Nucleus are Redistributed in Tinnitus. Neuroscience 391:91-103
Altschuler, R A; Kanicki, A; Martin, C et al. (2018) Rapamycin but not acarbose decreases age-related loss of outer hair cells in the mouse Cochlea. Hear Res 370:11-15
Yao, Hui; Hill, Sophie F; Skidmore, Jennifer M et al. (2018) CHD7 represses the retinoic acid synthesis enzyme ALDH1A3 during inner ear development. JCI Insight 3:
Zhao, Xiao-Feng; Kohen, Rafi; Parent, Rachel et al. (2018) PlexinA2 Forward Signaling through Rap1 GTPases Regulates Dentate Gyrus Development and Schizophrenia-like Behaviors. Cell Rep 22:456-470
Heeringa, Amarins N; Wu, Calvin; Shore, Susan E (2018) Multisensory Integration Enhances Temporal Coding in Ventral Cochlear Nucleus Bushy Cells. J Neurosci 38:2832-2843
Schvartz-Leyzac, Kara C; Pfingst, Bryan E (2018) Assessing the Relationship Between the Electrically Evoked Compound Action Potential and Speech Recognition Abilities in Bilateral Cochlear Implant Recipients. Ear Hear 39:344-358
Altschuler, Richard A; Halsey, Karin; Kanicki, Ariane et al. (2018) Small Arms Fire-like noise: Effects on Hearing Loss, Gap Detection and the Influence of Preventive Treatment. Neuroscience :
Devare, Jenna; Gubbels, Samuel; Raphael, Yehoash (2018) Outlook and future of inner ear therapy. Hear Res 368:127-135

Showing the most recent 10 out of 287 publications