Abstract

The Histology Core, under the co-direction of Drs. Paul Fuchs and Randy Reed, and staffed by Drs. Hakim Hiel and Mohamed Lehar, will provide training and guidance in a variety of histological procedures, as well as image acquisition and analysis using a core confocal microscope. Preparation for electron microscopy, ultrathin sectioning and image collection also will be provided. In addition to supporting those laboratories with qualifying grants, an important function of the Histology Core is to enable junior investigators to build their research programs in NIDCD-related areas. Finally, by serving as a source of expertise in inner ear and olfactory histology, the PSO enables novel disease and/or mouse models to be examined as they arise in other non-NIDCD-related research programs.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Center Core Grants (P30)
Project #
2P30DC005211-11
Application #
8400565
Study Section
Special Emphasis Panel (ZDC1-SRB-L (49))
Project Start
Project End
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
11
Fiscal Year
2012
Total Cost
$245,799
Indirect Cost
$94,071

  Institution

Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Lauer, Amanda M; Larkin, Gail; Jones, Aikeen et al. (2018) Behavioral Animal Model of the Emotional Response to Tinnitus and Hearing Loss. J Assoc Res Otolaryngol 19:67-81
Wu, Jingjing Sherry; Vyas, Pankhuri; Glowatzki, Elisabeth et al. (2018) Opposing expression gradients of calcitonin-related polypeptide alpha (Calca/Cgrp?) and tyrosine hydroxylase (Th) in type II afferent neurons of the mouse cochlea. J Comp Neurol 526:425-438
Jones, Aikeen; May, Bradford J (2018) Effects of Acoustic Environment on Tinnitus Behavior in Sound-Exposed Rats. J Assoc Res Otolaryngol 19:133-146
Zachary, Stephen; Nowak, Nathaniel; Vyas, Pankhuri et al. (2018) Voltage-Gated Calcium Influx Modifies Cholinergic Inhibition of Inner Hair Cells in the Immature Rat Cochlea. J Neurosci 38:5677-5687
Moglie, Marcelo J; Fuchs, Paul A; Elgoyhen, Ana Belén et al. (2018) Compartmentalization of antagonistic Ca2+ signals in developing cochlear hair cells. Proc Natl Acad Sci U S A 115:E2095-E2104
Cunningham, Christopher L; Wu, Zizhen; Jafari, Aria et al. (2017) The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells. Elife 6:
Lauer, Amanda M (2017) Minimal Effects of Age and Exposure to a Noisy Environment on Hearing in Alpha9 Nicotinic Receptor Knockout Mice. Front Neurosci 11:304
Johnson, Luke A; Della Santina, Charles C; Wang, Xiaoqin (2017) Representations of Time-Varying Cochlear Implant Stimulation in Auditory Cortex of Awake Marmosets (Callithrix jacchus). J Neurosci 37:7008-7022
Jones, Aikeen; May, Bradford J (2017) Improving the Reliability of Tinnitus Screening in Laboratory Animals. J Assoc Res Otolaryngol 18:183-195
Vyas, Pankhuri; Wu, Jingjing Sherry; Zimmerman, Amanda et al. (2017) Tyrosine Hydroxylase Expression in Type II Cochlear Afferents in Mice. J Assoc Res Otolaryngol 18:139-151

Showing the most recent 10 out of 139 publications