The Histology Core, under the co-direction of Drs. Paul Fuchs and Randy Reed, and staffed by Drs. Hakim Hiel and Mohamed Lehar, will provide training and guidance in a variety of histological procedures, as well as image acquisition and analysis using a core confocal microscope. Preparation for electron microscopy, ultrathin sectioning and image collection also will be provided. In addition to supporting those laboratories with qualifying grants, an important function of the Histology Core is to enable junior investigators to build their research programs in NIDCD-related areas. Finally, by serving as a source of expertise in inner ear and olfactory histology, the PSO enables novel disease and/or mouse models to be examined as they arise in other non-NIDCD-related research programs.

National Institute of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
Center Core Grants (P30)
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Special Emphasis Panel (ZDC1)
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Johns Hopkins University
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Wu, Jingjing Sherry; Young, Eric D; Glowatzki, Elisabeth (2016) Maturation of Spontaneous Firing Properties after Hearing Onset in Rat Auditory Nerve Fibers: Spontaneous Rates, Refractoriness, and Interfiber Correlations. J Neurosci 36:10584-10597
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Campbell, Dean P; Chrysostomou, Elena; Doetzlhofer, Angelika (2016) Canonical Notch signaling plays an instructive role in auditory supporting cell development. Sci Rep 6:19484
Martinez-Monedero, Rodrigo; Liu, Chang; Weisz, Catherine et al. (2016) GluA2-Containing AMPA Receptors Distinguish Ribbon-Associated from Ribbonless Afferent Contacts on Rat Cochlear Hair Cells. eNeuro 3:
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Lin, Chun-Chieh; Potter, Christopher J (2016) Editing Transgenic DNA Components by Inducible Gene Replacement in Drosophila melanogaster. Genetics 203:1613-28
Abt, Nicholas B; Lehar, Mohamed; Guajardo, Carolina Trevino et al. (2016) Intratympanic Iodine Contrast Injection Diffuses Across the Round Window Membrane Allowing for Perilymphatic CT Volume Acquisition Imaging. Otol Neurotol 37:403-7
Lin, Chun-Chieh; Potter, Christopher J (2016) Non-Mendelian Dominant Maternal Effects Caused by CRISPR/Cas9 Transgenic Components in Drosophila melanogaster. G3 (Bethesda) :
Diao, Fengqiu; Ironfield, Holly; Luan, Haojiang et al. (2015) Plug-and-play genetic access to drosophila cell types using exchangeable exon cassettes. Cell Rep 10:1410-21
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