The purpose of the Clinical Dental Research Core Center (CDRCC) is to provide facilities to permit clinical research relevant to pathogenesis, diagnosis, early detection, prevention, control, and treatment of oral diseases, disorders, and/or dysfunctions. The goal of the CDRCC is to significantly improve our capacity to deal with all aspects of these diseases and disorders through development of new ideas, concepts, treatment procedures, and diagnostic systems based on scientific knowledge rather than customary practice. We also seek to make maximum application of new knowledge and modern biotechnology, and to focus on the underserved, elderly, minority, disabled, and other special patient populations. The CDRCC will provide an environment and facilities for controlled clinical research of normal and abnormal body function. The setting will provide optimum supervision and protection of the rights and welfare of human subjects, encourage interdisciplinary collaboration between basic and clinical scientists, and provide unique opportunities for the study not only of large populations of patients with commonly encountered clinical disorders, but also of those patients not otherwise readily obtainable, with rate or unusual oral and dental diseases. The CDRCC will serve as a research training site for individuals in our residency and graduate training programs, especially those in NIDR-supported postdoctoral training programs. The CDRCC consists of five cores, including Administrative, Biometry, Clinical, Laboratory, and Imaging Cores. The CDRCC and its Cores are structured in a manner to maximally enhance communications and collaboration, and to carefully monitor program progress and pilot and feasibility research. Our proposal has several unique features. We incorporate the largest group of behavioral scientists in U.S. dental schools, an unusually large, diverse, and productive portfolio of funded ongoing research, and several large unique populations of patients such as hemophiliacs, phobic patients, and the largest group of orthodontic and full-mouth reconstruction cases with complete longitudinal documentation in the country. We have a major institutional commitment to provide a state- of-the-art clinical research facility in the School of Dentistry, and salary support for most involved faculty.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Center Core Grants (P30)
Project #
5P30DE009743-02
Application #
3101896
Study Section
Special Emphasis Panel (SRC (01))
Project Start
1990-09-30
Project End
1995-09-29
Budget Start
1991-09-30
Budget End
1992-09-29
Support Year
2
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Derouen, Timothy A; Wiesenbach, Carol (2012) The summer institute in clinical dental research methods: still going and growing after twenty years. J Dent Educ 76:1408-15
Smith, Jodi M; Wong, Craig S; Salamonik, Eva B et al. (2006) Sonic tooth brushing reduces gingival overgrowth in renal transplant recipients. Pediatr Nephrol 21:1753-9
Sherman, Jeffrey J; LeResche, Linda; Mancl, Lloyd A et al. (2005) Cyclic effects on experimental pain response in women with temporomandibular disorders. J Orofac Pain 19:133-43
Ramsay, Douglas S; Leroux, Brian G; Rothen, Marilynn et al. (2005) Nitrous oxide analgesia in humans: acute and chronic tolerance. Pain 114:19-28
Coolidge, T; Heima, M; Heaton, L J et al. (2005) The Child Dental Control Assessment (CDCA) in youth: reliability, validity and cross-cultural differences. Eur J Paediatr Dent 6:35-43
Persson, Rigmor E; Kiyak, Asuman H; Wyatt, Chris C I et al. (2005) Smoking, a weak predictor of periodontitis in older adults. J Clin Periodontol 32:512-7
Castillo, Jorge L; Milgrom, Peter (2004) Fluoride release from varnishes in two in vitro protocols. J Am Dent Assoc 135:1696-9
Persson, G Rutger; Persson, Rigmor E; Hollender, Lars G et al. (2004) The impact of ethnicity, gender, and marital status on periodontal and systemic health of older subjects in the Trials to Enhance Elders' Teeth and Oral Health (TEETH). J Periodontol 75:817-23
Naidu, Sinuba; Loughlin, Pat; Coldwell, Susan E et al. (2004) A randomized controlled trial comparing mandibular local anesthesia techniques in children receiving nitrous oxide-oxygen sedation. Anesth Prog 51:19-23
Frank, Richard P; Brudvik, James S; Noonan, Carolyn Jean (2004) Clinical outcome of the altered cast impression procedure compared with use of a one-piece cast. J Prosthet Dent 91:468-76

Showing the most recent 10 out of 95 publications