Abstract

The Clinical Research Core provides Affiliate Investigators with access to human volunteers, both diabetic and controls, for clinical research. Services include recruitment of volunteers for studies and obtaining blood or other specimens from research subjects and delivering these specimens to the appropriate laboratories. The Clinical Research Core has been crucial in supporting both investigations which require only a few subjects (or specimens) as well as those which require very large numbers of subjects. In addition to the Director and Associate Director, the Clinical Research Core staff includes one full time Research Study Coordinator and half-time Administrative Coordinator. Variable costs incurred by the Clinical Research Core are reimbursed as program income to the Core as part of a charge-back system to Affiliate Investigators.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK017047-27
Application #
6612275
Study Section
Special Emphasis Panel (ZDK1-GRB-7 (O1))
Project Start
2002-12-01
Project End
2007-11-30
Budget Start
Budget End
2003-11-30
Support Year
27
Fiscal Year
2003
Total Cost
$125,972
Indirect Cost

  Institution

Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Wall, Valerie Z; Barnhart, Shelley; Kanter, Jenny E et al. (2018) Smooth muscle glucose metabolism promotes monocyte recruitment and atherosclerosis in a mouse model of metabolic syndrome. JCI Insight 3:
Toledo, Frederico G S; Johannsen, Darcy L; Covington, Jeffrey D et al. (2018) Impact of prolonged overfeeding on skeletal muscle mitochondria in healthy individuals. Diabetologia 61:466-475
Ferreccio, Amy; Mathieu, Julie; Detraux, Damien et al. (2018) Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal. Cell Cycle 17:535-549
Mukamal, Kenneth J; Siscovick, David S; de Boer, Ian H et al. (2018) Metabolic Clusters and Outcomes in Older Adults: The Cardiovascular Health Study. J Am Geriatr Soc 66:289-296
Tang, Jingjing; Frey, Jeremy M; Wilson, Carole L et al. (2018) Neutrophil and macrophage cell surface CSF-1 shed by ADAM17 drives mouse macrophage proliferation in acute and chronic inflammation. Mol Cell Biol :
Lynch, Kristian F; Lee, Hye-Seung; Törn, Carina et al. (2018) Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident ?-cell autoantibodies. J Autoimmun 86:93-103
Parilla, Jacqueline H; Willard, Joshua R; Barrow, Breanne M et al. (2018) A Mouse Model of Beta-Cell Dysfunction as Seen in Human Type 2 Diabetes. J Diabetes Res 2018:6106051
Bornfeldt, Karin E; Kramer, Farah; Batorsky, Anna et al. (2018) A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis. Am J Pathol 188:343-352
Wang, Ke; Zelnick, Leila R; Hoofnagle, Andrew N et al. (2018) Alteration of HDL Protein Composition with Hemodialysis Initiation. Clin J Am Soc Nephrol 13:1225-1233
Bharmal, Nazleen H; McCarthy, William J; Gadgil, Meghana D et al. (2018) The Association of Religious Affiliation with Overweight/Obesity Among South Asians: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study. J Relig Health 57:33-46

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