The Diabetes Research Center at the University of Washington has existed for 38 years as part of a national program supported by NIH. It acts as the focal point and umbrella for diabetes research in the Greater Seattle area W .h the goal of promoting an environment of collaborative research on diabetes, obesity and related disorders by (a) providing support to affiliate investigators through its biomedical research cores, (b) sponsoring an enrichment program comprising lectures and symposia to Inform the community of the latest developments in the area, (c) conducting a small pilot and feasibility program that provides grant support for new investigators in diabetes research and to established investigators In other disciplines, (d) ensuring the development of young investigators by providing fellowships for salary support and training In Its research cores, and (e) developing new research methods and technologies for use by investigators. To accomplish this goal, the Center is organized around six biomedical research cores (Cell Function Analysis Core, Cellular and Molecular Imaging Core, Human Studies Core, Immunology and Inflammation Core, Quantitative and Functional Proteomics Core, and Viral Vector and Transgenic Mouse Core) and an Administrative Core that also administers the Pilot and Feasibility Program and the Enrichment Program. Along with the commitment of the University of Washington and other Seattle institutions of research space and additional financial support, the Diabetes Research Center is a dynamic and constantly evolving center that supports 95 Seattle-based affiliate investigators who are making important scientific contributions in the areas of (a) etiology, pathogenesis and treatment of type 1 diabetes, (b) pathophysiology and treatment of type 2 diabetes, (c) obesity and regulation of body weight/composition, (d) microvascular complications of diabetes, (e) inflammation, macrovascular and other complications of diabetes, and (f) clinical trials and large-scale epidemiologic studies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK017047-37
Application #
8435840
Study Section
Special Emphasis Panel (ZDK1-GRB-S (O2))
Program Officer
Hyde, James F
Project Start
1996-12-01
Project End
2017-11-30
Budget Start
2013-03-13
Budget End
2013-11-30
Support Year
37
Fiscal Year
2013
Total Cost
$1,543,570
Indirect Cost
$499,979
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Nishizawa, Tomohiro; Kanter, Jenny E; Kramer, Farah et al. (2014) Testing the role of myeloid cell glucose flux in inflammation and atherosclerosis. Cell Rep 7:356-65
Bornfeldt, Karin E (2014) 2013 Russell Ross memorial lecture in vascular biology: cellular and molecular mechanisms of diabetes mellitus-accelerated atherosclerosis. Arterioscler Thromb Vasc Biol 34:705-14
Ho, Jacqueline M; Anekonda, Vishwanath T; Thompson, Benjamin W et al. (2014) Hindbrain oxytocin receptors contribute to the effects of circulating oxytocin on food intake in male rats. Endocrinology 155:2845-57
Baskin, Denis G; Hewitt, Stephen M (2014) Improving the state of the science of immunohistochemistry: the Histochemical Society's standards of practice. J Histochem Cytochem 62:691-2
Orozco, S; Yatim, N; Werner, M R et al. (2014) RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis. Cell Death Differ 21:1511-21
Look AHEAD Research Group (2014) Eight-year weight losses with an intensive lifestyle intervention: the look AHEAD study. Obesity (Silver Spring) 22:5-13
Martins-Mendes, Daniela; Monteiro-Soares, Matilde; Boyko, Edward John et al. (2014) The independent contribution of diabetic foot ulcer on lower extremity amputation and mortality risk. J Diabetes Complications 28:632-8
Durinovic-Belló, Ivana; Gersuk, Vivian H; Ni, Chester et al. (2014) Avidity-dependent programming of autoreactive T cells in T1D. PLoS One 9:e98074
Kratz, Mario; Marcovina, Santica; Nelson, James E et al. (2014) Dairy fat intake is associated with glucose tolerance, hepatic and systemic insulin sensitivity, and liver fat but not ?-cell function in humans. Am J Clin Nutr 99:1385-96
Duffield, Jeremy S (2014) Cellular and molecular mechanisms in kidney fibrosis. J Clin Invest 124:2299-306

Showing the most recent 10 out of 621 publications