The Enrichment Program supports the overall mission of the Penn DRC to prevent, treat, and cure diabetes. Its goals are to ensure that the DRC investigators from different departments and locations interact frequently and productively, that new scientific knowledge related to diabetes is disseminated to DRC investigators, and that the importance of diabetes research is recognized in the Philadelphia area. To achieve these goals, the Enrichment Program has the following Specific Aims;1. Disseminate new diabetes research knowledge;2) Foster interactions among DRC investigators;3) Catalyze interdisciplinary interactions;4) Foster the next generation of diabetes researchers;and 5) Increase awareness of the Penn DRC and the importance of diabetes research. The high scientific quality of the Enrichment Program's activities attracts not only Penn DRC members, but other members of the research community to lectures and events that increase awareness of Penn DRC cores and diabetes research. In addition, lay-oriented community events are hosted and designed to educate the public about the devastating epidemic of diabetes, and the importance of diabetes research at the Penn DRC and elsewhere to preventing and curing these diseases. In sum, the Enrichment Program of the Penn DRC plays a vital role in advancing the exchange of knowledge about diabetes, catalyzing interdisciplinary interactions and research in the scientific community it serves, and enhancing awareness of exciting diabetes research aimed at a cure at a time when the disease is rampant and increasingly threatening the health of people in Philadelphia and across the United States.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK019525-36
Application #
8310454
Study Section
Special Emphasis Panel (ZDK1-GRB-S (J1))
Project Start
Project End
Budget Start
2012-05-15
Budget End
2013-03-31
Support Year
36
Fiscal Year
2012
Total Cost
$20,800
Indirect Cost
$7,800
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Mukherjee, Sarmistha; Chellappa, Karthikeyani; Moffitt, Andrea et al. (2017) Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration. Hepatology 65:616-630
Oslund, Rob C; Su, Xiaoyang; Haugbro, Michael et al. (2017) Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate. Nat Chem Biol 13:1081-1087
Emmett, Matthew J; Lim, Hee-Woong; Jager, Jennifer et al. (2017) Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge. Nature 546:544-548
Carr, Rotonya M; Dhir, Ravindra; Mahadev, Kalyankar et al. (2017) Perilipin Staining Distinguishes Between Steatosis and Nonalcoholic Steatohepatitis in Adults and Children. Clin Gastroenterol Hepatol 15:145-147
Lee, Robert J; Hariri, Benjamin M; McMahon, Derek B et al. (2017) Bacterial d-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells. Sci Signal 10:
Hariri, Benjamin M; McMahon, Derek B; Chen, Bei et al. (2017) Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor. J Biol Chem 292:8484-8497
Zhu, Lu; AlmaƧa, Joana; Dadi, Prasanna K et al. (2017) ?-arrestin-2 is an essential regulator of pancreatic ?-cell function under physiological and pathophysiological conditions. Nat Commun 8:14295
Lu, Wenyun; Su, Xiaoyang; Klein, Matthias S et al. (2017) Metabolite Measurement: Pitfalls to Avoid and Practices to Follow. Annu Rev Biochem 86:277-304
Soccio, Raymond E; Li, Zhenghui; Chen, Eric R et al. (2017) Targeting PPAR? in the epigenome rescues genetic metabolic defects in mice. J Clin Invest 127:1451-1462
Susiarjo, Martha; Xin, Frances; Stefaniak, Martha et al. (2017) Bile Acids and Tryptophan Metabolism Are Novel Pathways Involved in Metabolic Abnormalities in BPA-Exposed Pregnant Mice and Male Offspring. Endocrinology 158:2533-2542

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