The objective of the Functional Genomics Core is to provide state of the art experiment planning, sample preparation, quality assessment, microarray, DNA sequencing, and data analysis services to DRC members.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK019525-37
Application #
8469478
Study Section
Special Emphasis Panel (ZDK1-GRB-S)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
37
Fiscal Year
2013
Total Cost
$166,412
Indirect Cost
$61,810
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Rickels, M R; Markmann, E; Naji, A (2018) Successful pregnancies after islet transplantation for type 1 diabetes. Am J Transplant :
Friedman, Elliot S; Li, Yun; Shen, Ting-Chin David et al. (2018) FXR-Dependent Modulation of the Human Small Intestinal Microbiome by the Bile Acid Derivative Obeticholic Acid. Gastroenterology 155:1741-1752.e5
Rickels, Michael R; DuBose, Stephanie N; Toschi, Elena et al. (2018) Mini-Dose Glucagon as a Novel Approach to Prevent Exercise-Induced Hypoglycemia in Type 1 Diabetes. Diabetes Care 41:1909-1916
Jang, Cholsoon; Hui, Sheng; Lu, Wenyun et al. (2018) The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids. Cell Metab 27:351-361.e3
Juliana, Christine A; Yang, Juxiang; Cannon, Corey E et al. (2018) A PDX1-ATF transcriptional complex governs ? cell survival during stress. Mol Metab 17:39-48
McKee, Sarah E; Zhang, Sisi; Chen, Li et al. (2018) Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain. J Neurochem 145:362-373
Wangensteen, Kirk J; Wang, Yue J; Dou, Zhixun et al. (2018) Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform. Hepatology 68:663-676
Brown, Justin C; Damjanov, Nevena; Courneya, Kerry S et al. (2018) A randomized dose-response trial of aerobic exercise and health-related quality of life in colon cancer survivors. Psychooncology 27:1221-1228
Wooldridge, Amy L; Bischof, Robert J; Liu, Hong et al. (2018) Late-gestation maternal dietary methyl donor and cofactor supplementation in sheep partially reverses protection against allergic sensitization by IUGR. Am J Physiol Regul Integr Comp Physiol 314:R22-R33
Kim, Boa; Jang, Cholsoon; Dharaneeswaran, Harita et al. (2018) Endothelial pyruvate kinase M2 maintains vascular integrity. J Clin Invest 128:4543-4556

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