The Administrative Component supports the overall mission of the Penn DRC to prevent, treat, and cure diabetes mellitus. Its goal is to ensure that the DRC operates smoothly, effectively, and ethically while creating and nurturing the best possible environment for interdisciplinary basic and clinical diabetes research among its participating investigators. To achieve this goal, the DRC Administrative Component has the following Speciifc Aims: 1) Provide vision and leadership for the Penn DRC;2) Provide scientific direction for Penn DRC cores and activities;3) Foster interactions among DRC investigators;4) Represent the Penn DRC and its mission within and outside the University of Pennsylvania;5) Oversee the finances of the Penn DRC;and 6) Foster the next generation of diabetes researchers. The Administrative Component governs the DRC via a defined organizational structure that includes the Director and Associate Director, an Executive Committee, a Committee of Core Directors, and external as well as internal advisory boards. It coordinates and publicizes the Scientific Cores, Pilot and Feasibility Grant Program, and Enrichment Program that advance diabetes research by providing unique resources and facilitating communication and collaboration among the diverse group of diabetes-oriented basic and translational researchers that comprise the Penn DRC Research Base. The strong and responsive Administrative Component is critical to maintain the diabetes research program at the Penn DRC at the forefront of biomedical science.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK019525-38
Application #
8638927
Study Section
Special Emphasis Panel (ZDK1-GRB-S)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
38
Fiscal Year
2014
Total Cost
$528,937
Indirect Cost
$96,661
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Mukherjee, Sarmistha; Chellappa, Karthikeyani; Moffitt, Andrea et al. (2017) Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration. Hepatology 65:616-630
Oslund, Rob C; Su, Xiaoyang; Haugbro, Michael et al. (2017) Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate. Nat Chem Biol 13:1081-1087
Emmett, Matthew J; Lim, Hee-Woong; Jager, Jennifer et al. (2017) Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge. Nature 546:544-548
Carr, Rotonya M; Dhir, Ravindra; Mahadev, Kalyankar et al. (2017) Perilipin Staining Distinguishes Between Steatosis and Nonalcoholic Steatohepatitis in Adults and Children. Clin Gastroenterol Hepatol 15:145-147
Lee, Robert J; Hariri, Benjamin M; McMahon, Derek B et al. (2017) Bacterial d-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells. Sci Signal 10:
Hariri, Benjamin M; McMahon, Derek B; Chen, Bei et al. (2017) Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor. J Biol Chem 292:8484-8497
Zhu, Lu; AlmaƧa, Joana; Dadi, Prasanna K et al. (2017) ?-arrestin-2 is an essential regulator of pancreatic ?-cell function under physiological and pathophysiological conditions. Nat Commun 8:14295
Lu, Wenyun; Su, Xiaoyang; Klein, Matthias S et al. (2017) Metabolite Measurement: Pitfalls to Avoid and Practices to Follow. Annu Rev Biochem 86:277-304
Soccio, Raymond E; Li, Zhenghui; Chen, Eric R et al. (2017) Targeting PPAR? in the epigenome rescues genetic metabolic defects in mice. J Clin Invest 127:1451-1462
Susiarjo, Martha; Xin, Frances; Stefaniak, Martha et al. (2017) Bile Acids and Tryptophan Metabolism Are Novel Pathways Involved in Metabolic Abnormalities in BPA-Exposed Pregnant Mice and Male Offspring. Endocrinology 158:2533-2542

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