The mission of the Hormone &Metabolite Core is to assist investigators by performing uniform and standardized assays of various plasma metabolites, hormones, adipokines and cytokines in rodent models and human studies related to the regulation of obesity and co-morbidities, energy balance, eating disorders and nutrition related problems. The assay services provided within this Core provide an integrative framework for understanding obesity and associated disorders in glucose and lipid metabolism. In addition, the data obtained directly relate to and integrate with the analyses performed in the Body Composition, Animal Energy Balance Phenotyping, the Adipocyte and the Molecular Genetic Cores ofthe Center. The services provided at the HMC are best based in a Core Laboratory because they require special instrumentation and methodology, which would be difficult or impracticably expensive to establish in the laboratories of the individual investigators who are Members ofthe NYONRC.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK026687-33
Application #
8463175
Study Section
Special Emphasis Panel (ZDK1-GRB-2)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
33
Fiscal Year
2013
Total Cost
$195,579
Indirect Cost
$41,422
Name
St. Luke's-Roosevelt Institute for Health Sciences
Department
Type
DUNS #
623216371
City
New York
State
NY
Country
United States
Zip Code
10019
Iqbal, Niloy Jafar; Lu, Zhonglei; Liu, Shun Mei et al. (2018) Cyclin-dependent kinase 4 is a preclinical target for diet-induced obesity. JCI Insight 3:
Martin Carli, Jayne F; LeDuc, Charles A; Zhang, Yiying et al. (2018) FTO mediates cell-autonomous effects on adipogenesis and adipocyte lipid content by regulating gene expression via 6mA DNA modifications. J Lipid Res 59:1446-1460
Blumenfeld, Nicole R; Kang, Hwan June; Fenzl, Anna et al. (2018) A direct tissue-grafting approach to increasing endogenous brown fat. Sci Rep 8:7957
Ravussin, Yann; Edwin, Ethan; Gallop, Molly et al. (2018) Evidence for a Non-leptin System that Defends against Weight Gain in Overfeeding. Cell Metab 28:289-299.e5
Shechter, Ari; Kim, Elijah Wookhyun; St-Onge, Marie-Pierre et al. (2018) Blocking nocturnal blue light for insomnia: A randomized controlled trial. J Psychiatr Res 96:196-202
Sui, Lina; Danzl, Nichole; Campbell, Sean R et al. (2018) ?-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells. Diabetes 67:26-35
Laferrère, Blandine; Pattou, François (2018) Weight-Independent Mechanisms of Glucose Control After Roux-en-Y Gastric Bypass. Front Endocrinol (Lausanne) 9:530
Lin, Belle Yanyu; Genden, Karma; Shen, Wei et al. (2018) The prevalence of obesity and metabolic syndrome in Tibetan immigrants living in high altitude areas in Ladakh, India. Obes Res Clin Pract 12:365-371
Heymsfield, S B; Peterson, C M; Bourgeois, B et al. (2018) Human energy expenditure: advances in organ-tissue prediction models. Obes Rev 19:1177-1188
Shah, Ankit; Levesque, Kiarra; Pierini, Esmeralda et al. (2018) Effect of sitagliptin on glucose control in type 2 diabetes mellitus after Roux-en-Y gastric bypass surgery. Diabetes Obes Metab 20:1018-1023

Showing the most recent 10 out of 809 publications