Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK027651-29
Application #
8320610
Study Section
Special Emphasis Panel (ZDK1-GRB-7 (J1))
Project Start
1997-04-23
Project End
2015-03-31
Budget Start
2012-05-08
Budget End
2013-03-31
Support Year
29
Fiscal Year
2012
Total Cost
$125,578
Indirect Cost
$45,599
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Dasenbrook, Elliott C; Konstan, Michael W; VanDevanter, Donald R (2015) Association between the introduction of a new cystic fibrosis inhaled antibiotic class and change in prevalence of patients receiving multiple inhaled antibiotic classes. J Cyst Fibros 14:370-5
Than, B L N; Goos, J A C M; Sarver, A L et al. (2014) The role of KCNQ1 in mouse and human gastrointestinal cancers. Oncogene 33:3861-8
Xu, Weiling; Janocha, Allison J; Leahy, Rachel A et al. (2014) A novel method for pulmonary research: assessment of bioenergetic function at the air-liquid interface. Redox Biol 2:513-9
Boyle, Michael P; Bell, Scott C; Konstan, Michael W et al. (2014) A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation: a phase 2 randomised controlled trial. Lancet Respir Med 2:527-38
Doring, Gerd; Bragonzi, Alessandra; Paroni, Moira et al. (2014) BIIL 284 reduces neutrophil numbers but increases P. aeruginosa bacteremia and inflammation in mouse lungs. J Cyst Fibros 13:156-63
Spilker, Theodore; Leber, Amy L; Marcon, Mario J et al. (2014) A simplified sequence-based identification scheme for Bordetella reveals several putative novel species. J Clin Microbiol 52:674-7
Zaman, Khalequz; Bennett, Deric; Fraser-Butler, Maya et al. (2014) S-Nitrosothiols increases cystic fibrosis transmembrane regulator expression and maturation in the cell surface. Biochem Biophys Res Commun 443:1257-62
VanDevanter, Donald R; Pasta, David J; Konstan, Michael W (2014) Improvements in lung function and height among cohorts of 6-year-olds with cystic fibrosis from 1994 to 2012. J Pediatr 165:1091-1097.e2
Caretti, Anna; Bragonzi, Alessandra; Facchini, Marcella et al. (2014) Anti-inflammatory action of lipid nanocarrier-delivered myriocin: therapeutic potential in cystic fibrosis. Biochim Biophys Acta 1840:586-94
Kerem, Eitan; Konstan, Michael W; De Boeck, Kris et al. (2014) Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial. Lancet Respir Med 2:539-47

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